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Flashcards in Theories of Aging Deck (14):
1

What are the two causes of the loss of homeostasis?

1. Breakdown in maintenance of specific molecular structures/pathways
2. overall organ system stress

2

Is there agreement on the definition of aging?

No

3

What is the disposable body theory?

Birth, breed, death

4

What is the mutation accumulation theory?

Every insult has the potential to turn on problems

5

What is the targeted DNA damage theory of aging?

Cumulative deletions, mutations, and translocations

6

What is the mitochondrial theory of aging?

Altered mito = more ROS

7

What is the telomere theory of aging?

Loss of telomeres

8

What is the error catastrophe theory of aging?

Cumulative errors in RNA and protein synthesis

9

What is the accumulation theory?

Accumulation of abnormal proteins that are not removed

10

What is a commonly missed disease in the elderly?

Hypothyroidism

11

What are the 6 premature aging syndromes?

1. Down
2. Werner
3. Progeria
4. Klinefelter
5. Turner
6. Myotonic dystrophy

12

What is the Ca theory of aging?

Abnormal Ca movements cause free radical damage, etc

13

What is the neuro-aging theory?

All cells undergo nervous system degeneration, which changes hormonal release, leading to decline in cell function

14

What is the most influential factor of how a pt ages?

How they handle the changes, and attitude