Thiazide + Thiazide-like Diuretics Flashcards Preview

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Flashcards in Thiazide + Thiazide-like Diuretics Deck (5)
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1

Examples

Bendroflumethiazide
Chlortalidone
Indapamide

2

Mode of action

Thiazide sensitive Na/Cl co-transporter in DCT
Inhibitor
Reduces Na+ and Cl- reabsorption
Removal of salt, vasodilator action

3

Indications

Hypertension
Oedema

4

Adverse drug reactions

Oto + Nephrotoxicity
Hypotension
Hyponatraemia/kalaemia
Hypercalcaema
Increase pH and urea
AKI
Dehydration
Hyperglyceamia

5

Prescribing Advice

eGFR >30
X w/ Aminoglycoside, NSAIDs, Lithium, SSRI