Thyroid Disorders (Exam 3) Flashcards
(42 cards)
Continuum of Thyroid Dysfunction
Euthyroid State
Hyperthyroidism — Thyroid Storm
Hypothyroidism – Myxedema Coma
Thyroid Storm is interchangable with
Acute thyrotoxicosis
Thyrotoxic Crisis
Thyroid Review
Thyroid gland is control by secretion of TSH by Pituitary gland
TSH stimulates release of T4 (thyroxine) (inactive)
T4 is converted into T3 (triiodothyronine) Active
T3 Activates and energises all cells of the body
TSH is the shut off valve
Goiter
Enlarged thyroid gland
Goiter can be a result of
Overactive or underactive thyroid
Hyperthyroidism disorder
Graves Disease (75%) (Autoimmune)
Toxic multo-nodular goiter
Hyperthyroidism Hormones (Graves)
Increase T3 & T4
Decrease TSH
Hypothyroidism
Hashimoto’s thyroiditis
Hypothyroidism Hormones (hashimotos)
Decrease T3 and T4
Increase TSH
Goiter Can be caused by
Thyroiditis
Benign thyroid Nodules
Malignancy
Iodine deficiency
Toxic Goiter
Goiter with HYPERthyroidism
Non-toxic Goiter
Goiter with normal thyroid levels
(autoimmune problem)
Iodine Deficiency
Iodine is needed for synthesis of thyroid hormones
ONLY thyroid can uptake iodine
Deficiency occurs in parts of the world where it is insufficient in the diet
HORMONES CAN NOT BE SYNTHESIZED
Iodine Containing Foods
Yogurt
Milk
Eggs
Iodized Salt
Hyperthyroidism: Clinical S/S
-Metabolism
-Increase HR - murmurs - dysrhythmias - angina - palps
-Increase RR - DOE
-Weight loss
-Increase peristalsis
-Diarrhea
-Memory lapses
-Short attention span
-Hair loss (alopecia)
-Palmar erythema (red palms)
-Fine silky hair
-Diaphoresis
-Warm - moist skin
-VITILIGO
-BRUIT over gland
-Goiter
-EXOPHTHALMOS (Bulging Eyes)
Thyrotoxicosis
Excess thyroid hormone in body
Acute Thyrotoxicosis - Thyrotoxic Crisis - Thyroid Storm
Acute and severe (rare) (death rare when treat early)
Results from stressors in patient with pre-existing hyperthyroidism
Patient having thyroidectomy are at risk (manipulation of hyperactive thyroid)
Management of Hyperthyroidism: Durgy Therapy
Anti-thyroid Medication
-methimazole
Iodine therapy
-SSKI and Lugol’s solution
Beta Blocker
Hyperthyroidism: Antithyroid Medicaiton
Methimazole
-Improvement seen 1-2 weeks after start
-Results take 4-8 weeks
Hyperthyroidism: Iodine Therapy
SSKI and Lugol’s Solution
Used to prepare the patient for a thyroidectomy
Give rapidly in large dose: Inhibits T3 and T4 and decreases vascularity of thyroid gland.
Makes surgery easier and safer
Hyperthyroidism: Beta-blockers
Use for symptomatic relief of thyrotoxicosis
Hyperthyroidism: Treatment of choice
Radioactive Iodine Therapy 131
T/F: 60% of people with hashimoto’s disease received Radioactive Iodine Therapy 131?
False
People with graves disease get this therapy because the hyperactive thyroid uptakes the radioactive iodine
Radioactive Iodine Therapy 131 is for
Non pregnant adults