Topic 6 -12 Flashcards
(10 cards)
What is the primary role of the cell-mediated immune response?
To destroy cells infected by pathogens, particularly viruses.
This response results in the production of T killer cells that prevent virus replication.
What type of cells are produced during the cell-mediated immune response?
T killer cells.
These cells are responsible for destroying infected host cells.
What is the function of MHCs in the immune response?
To present antigens from infected cells as Antigen-Presenting Cells (APCs).
This process is crucial for activating T killer cells.
List the similarities between humoral and cell-mediated immune responses.
- Both are specific to a particular antigen.
- Both require formation of APCs and the presence of MC.
- Both involve clonal selection.
- Both involve clonal expansion.
- Both involve differentiation of cells following activation by T helper cells.
MC refers to Major Histocompatibility Complex.
What is clonal selection in the context of immune responses?
The activation of only those cells which recognize the antigen.
It ensures that the immune response is specific.
Define clonal expansion.
The proliferation of the cells needed to produce a large number of immune cells.
This process ensures an adequate response to the pathogen.
What happens to T killer cells after activation by cytokines?
They divide and differentiate into active T killer cells and T killer memory cells.
Memory cells are important for long-term immunity.
What is the role of active T killer cells in the immune response?
They bind to infected cells presenting antigens on MHCs and cause lysis.
This action leads to the death of the infected cell.
True or False: The cell-mediated immune response is non-specific to antigens.
False.
The response is specific to a particular antigen.
Fill in the blank: The active T killer cell releases _______ that cause lysis in the infected cell.
chemicals.
These chemicals create pores in the membrane of the infected cell.
