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1

Marker for colorectal cancer?

CEA

2

MOA of Acetazolamide?

carbonic anhydrase inhibitor that acts at the proximal convoluted tubule and impairs bicarbonate reabsorption

3

Name a complication of Acetazolamide use

renal tubular acidosis type 2

4

HPV subtypes responsible for condyloma acuminata

6 and 11

5

HPV subtypes responsible for cervical cancer

16,18,31,33

6

At what age does schizophrenia usually present?

20's

7

How long do + and - schizo sx need to last to be considered schizophrenia?

at least 6 months

8

Pt presents with hemiparesis/paralysis of the face and arm moreso than the LE. Where was the stroke?

contralateral MCA

9

Pt presents with hemineglect and aphasia. Where was the stroke?

left MCA

10

Which structures are usually compromised in ovarian torsion?

infundibulopelvic ligament (suspensory ligament of ovary); houses Ovarian A. and V.

is an emergency

11

Drug of choice to reduce inflammation in ulcerative colitis?

sulfasalazine

12

Fever, night sweats, and weight loss are sx of what?

TB

13

Caseous necrosis in which lymph nodes is indicative of TB?

hilar

14

Which antibodies are specific for limited cutaneous scleroderma?

anti-centromere antibodies

15

Name some H2 receptor antagonists (proton pump inhibitors)

ranitidine, cimetidine, nizatidine, famotidine

16

Name a GI side effect common in diabetics

gastroparesis due to autonomic damage

17

What drug is used to treat gastroparesis in DM and how does it work?

metoclopramide; stimulates peristalsis by blocking dopamine receptors; can have extrapyramidal side effects

18

What is Efaviranez?

non-nucleoside reverse transcriptase inhibitor

19

Does efaviranez incorporate itself into viral DNA?

no

20

How does phenytoin cause folate deficiency?

it inhibits intestinal conjugase, an enzyme necessary to convert folate into an absorbable form in the jejunum

21

Name a type of agar specifically used to grow Neisseria gonorrhoeae

Thayer-Martin chocolate agar

22

What loop diuretic is used in people with sulfa allergy?

ethacrynic acid

23

How is muscle contraction initiated in the myocyte?

calcium binds troponin, which causes a conformational change in troponin, causing tropomyosin to move and expose the myosin binding sites on actin

24

What type of virus in Rhino virus?

picornavirus

25

What are some characteristics of Rhinovirus?

picornavirus, non-enveloped, positive sense RNA virus in which the genome acts directly as mRNA. Has antigenic variability

26

What are sx of granulomatosis with polyangiitis (Wegners)?

mucosal ulcers, sinusitis with rapidly progressive renal failure

(also lung involvement) organs involved shaped as a "C"

27

What marker is elevated in granulomatosis with polyangiitis?

C-ANCA

28

What is elevated in folate deficiency?

homocysteine

29

What is elevated in B12 deficiency?

homocysteine AND methylmalonic acid

30

What is specificity?

the ability to detect the absence of disease