Flashcards in Tumor Markers Deck (24):
This term means swelling
This is defined as new growth.
this type of neoplasm is autonomous, slow-growing; may be locally invasive but does not spread to distant organs
this type of neoplasm is autonomous, rapidly-growing; locally invasive and spreads (metastasizes) to distant organs
This term means independent of the usual control mechanisms.
This is a malignant neoplasm.
In benign endocrine tumors, the mass of tumor in the body can be estimated by measuring the concentration of what?
normal cell product in blood
The mass of most _______ tumors must be assessed by measuring the concentration of a molecules known to be increased in patients with a specific malignancy.
this neoplasm has some characteristics of the tissue of origin
this neoplasm has few characteristics of the tissue of origin
this neoplasm has no characteristics of the tissue of origin, morphologically or functionally
anaplastic (without form) neoplasm
This syndrome has symptoms of a cancer patient that are not a result of local neoplastic growth/spread and are not a result of metastases to distant sites.
What are the three most common paraneoplastic syndromes?
1 Cushing's syndrome
3 syndrome of inappropriate anti-diuretic hormone (SIADH)
What are the underlying cancers of Cushing's syndrome?
pancreas and lung
What are the casual substances of cushing's syndrome ?
ACTH or ACTH-like substances produced by the cancer cells
What are the typical lab results of Cushing's syndrome?
excess cortisol release, abnormal FBG, glucose intolerance, and an increased serum cortisol concentration
What are the underlying cancers of hypercalcemia?
lung, breast, and ovary
What is the casual substance of hypercalcemia?
parathyroid hormone related protein
What are the lab results for hypercalcemia?
PTH increased OR PTH related protein detected
What are the underlying cancers of SIADH?
brain and lung
What is the casual substance of SIADH?
What are the lab tests for SIADH?
sodium and osmolality, measured in both serum and urine
This is a substance produced by a tumor, or by the host in response to a tumor, that is used to differentiate a tumor from normal tissue or to determine the presence of a tumor based on measurements in the blood or secretions.