Tutorial 1 Flashcards

1
Q

Bonds required for primary structure?

A

Peptide covalent bonds.

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2
Q

Interactions required to form secondary structures?

A

Hydrogen bonds from the backbone.

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3
Q

Bonds between R groups are important for?

A

Tertiary and quaternary structures.

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4
Q

The promotor consists of?

A

-35 box to the -10r box.

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5
Q

Where does transcription start?

A

In the +1 site.

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6
Q

Point mutation?

A

Change in a single base in DNA. It can be minimal or severe (change in start or stop codon)

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7
Q

How many replication rounds does it take for a mutation to affect both strands?

A

2 rounds.

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8
Q

Silent mutations?

A

Mutations that get ignored because of wobble effect since it changes the third base pair of a codon.

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9
Q

Missense mutations?

A

A point mutation that actually changes the amino acid (the mutation occurs in the first or second base pair of a codon).

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10
Q

Nonsense mutations?

A

Point mutation that creates a new stop codon.

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11
Q

Deletion mutation?

A

When a base pair gets deleted.

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12
Q

Frameshift mutation?

A

When a base pair gets deleted and the entire sequence shifts.

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