** what are the most abundant amino acids in serum.
Glutamine and alanine
What are the essenital AA?
"Pvt. Tim Hall"
___ separate transporters of AA from the gut into intestinal epithelial cells
Hartnup’s Disease sx?
4D’s: Diarrhea, Dermatitis, Dementia, Death)
how is Hartnup’s Disease dx?
diarrhea, dermatitis, dementia, death with HIGH LEVELS OF NEUTRAL OR AROMATIC AA IN URINE
what is the defect in Cysinuria?
A defect in the transport system for basic amino acids and cystine (a disulfide- linked dimer of cysteine) from the gut and the renal tubules.
crystals formed by cystine can lead to UTI AND KIDNEY STONES
Glycine is converted by____ to serine
Glycine is converted by serine hydroxymethyltransferase to _____
Glycine is converted by serine hydroxymethyltransferase to serine, which is then converted to ____
Glycine is converted by serine hydroxymethyltransferase to serine
was is taken up? what is removed?
how can glyceine be broken down into Co2 and free ammonia?
Glycine Cleavage Enzyme (glycine synthase, run in reverse)
glycine---> co2 and NH4
what is given off
via GLYCINE CLEAVAGE ENZYME
CO2 + NH4