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Flashcards in Respiratory Chain Deck (45)
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1

Oxidation- reduction proteins  are located within the

mitocondrial membrane

2

This respiratory chain serves to break up the 52 kcal/mole available from the flow of ___from NADH to O2 into approximately three equal amounts.

2 electrons 

3

This respiratory chain serves to break up the 52 kcal/mole available from the flow of 2 electrons from NADH to O2

 

the majority of this energy is used to

form atp

4

The rate of respiration is controlled by the availability of ___

ADP 

5

Advantages of a membrane-bound respiratory chain  chain

(1) Kinetics: Not limited by the rate of diffusion; no mobile carrier needed.


(2) Stability of intermediates: reduced fuel will be converted to energy stored in an electrochemical gradient. For a gradient you need two compartments. The membrane provides such a boundary.

6

Flavins:___donor/acceptor 

 two-electron 

7

Flavins have a ___ addition

1,4

8

NADH dehydrogenase contains tightly bound

FMN

9

Succ. Dehyd. contains covalently bound ___

FAD

10

Iron-Sulfur Centers: Accept e-1s from 

 Flavins and Q

11

iron sulfate centers may have ___ irons per
center

2-4

12

Iron-Sulfur Centers have how many electron donor/acceptors?

They may have 2-4 irons per
center, but they are one-electron donor/acceptors. 

13

Acidification of iron sulfar centers leads to →

 H2S gas

14

Ubiquinone: ___-electron donor/acceptor

two

15

ubiquinone Functions as an electron ___.

buffer

16

Ubiquinone has ___ additon

1,6

17

Hemes: ___-electron donor/acceptors

one

18

The heme is covalently attached to two ____ side chains in cytochromes c and c1.

cysteine

19

The iron atom of the heme group in cytochrome c coordinates to a 

methionine and a histidine side chain in addition to the 4 porphyrin-ring nitrogens.

20

Copper Centers: one-electron donor/acceptors in

cytochrome oxidase

21

Copper center A contains ___ Cu

two

22

what forms the forms the O2 binding site at the end of the Respiratory Chain? 

1.  Copper center B

2. the heme iron of Cyt a3

in cytochrome oxidase

23

what is in cytosohome oxidase? 

 CuA, CuB,  Cyt a, Cyt a3

24

path of electron flow in cytochrome oxidase?

to CuA -> cytocrhome a -> cytochrome 3 -> cuB

25

The participation of two copper centers and two heme irons in cytochrome oxidase may be required in order to  (2)

1. rapidly deliver 4e- to O2

2. avoid production of H2O2 and superoxides.

26

For efficient flow, components should be arranged in order of ___ 

INCREASING ELECTRON AFFINITY

27

order of the components of the respiratory chain?

Nad -> Q -> b -> C -> a

28

___ contains three catalytic sites for ATP synthesis

F1

29

____ is a hydrophobic complex that transverses the membrane and carries protons from one site to the other.

Fo

30

 the endergonic synthesis of ATP is obligatorily coupled to the ___

exergonic redox reactions

 

the reverse is also true