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Pathophysiology > Unit 2 - part 1 > Flashcards

Unit 2 - part 1 Flashcards

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1
Q

What are the 3 NORMAL layers of oral mucosa?

A

Oral Epi (OE) Lamina Propria (gingival connective tissue) Submucosa

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2
Q

_______ tissue covers the hard palate and the attached and free gingiva?

A

Masticatory

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3
Q

The cheeks and the soft palate are covered with _____ mucosa

A

lining

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4
Q

Non-Masticatory mucosa covers what surfaces?

A

Vestibules Alveolar Mucosa

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5
Q

All cellular mitosis occurs where?

A

Basal Lamina

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6
Q

What structure separates the OE from the connective tissue?

A

Basement Membrane

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7
Q

What term is used to describe the process of cellular growth going from the bottom layer (basement membrane) up to the surface?

A

Orthokeratinization

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8
Q

Cells form on the _____ _______ and are seen as round cells?

A

basal lamina

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9
Q

Cells go from being round in shape to being “squished” and have projections (desmosoomes) sticking out of them….this layer is called the?

A

Prickle layer

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10
Q

What layer comes after the prickle layer?

A

Granular layer

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11
Q

What is the 4th layer called and what type of tissue has a 4th layer?

A

Keratin Layer Masticatory

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12
Q

The average amount of days for a cell to go from “birth” to “death” is?

A

25 days

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13
Q

The lamina propria contains what cells?

A

Fibroblasts Macrophage Mast

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14
Q

The submucosa contains?

A

salivary glands blood vessels muscles

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15
Q

What is the term for a epithelium projection into the connective tissue?

A

Rete Pegs

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16
Q

What is a common area to have hyperkeratosis?

A

Linea Alba (cheek bite)

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17
Q

Why does hyperkeratosis appear white in the mouth?

A

because it absorbs more fluid and reflects back a white color

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18
Q

What is the fancy name for a cheek bite?

A

Morsicatio Buccarum

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19
Q

71% of all white lesions of the oral mucosa are?

A

Benign Hyperkeratosis

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20
Q

A _______ is a white, opaque, leathery lesion NOT clinically identifiable from other white lesions?

A

Leukoplakia

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21
Q

If someone has a white lesion in ________ it automatically needs to be biopsied and taken care of cause it isn’t normal?

A

floor of mouth

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22
Q

A dysplastic leukoplakia is a white spot with ________

A

dyskeratosis

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23
Q

Dyskeratosis is often associated with?

A

malignancy

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24
Q

A THIN white keratotic film usually over the lower lip is termed a?

A

Solar Cheilosis

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25
Solar Cheilosis predisposes to?
cancer of lip
26
What is the most common zone for skin cancers?
Ala-traga zone (head of bald guys also)
27
Solar Cheilosis is also called?
Actinic keratosis
28
White sponge nevus is a ________ keratosis with a _________ white folded \_\_\_\_\_\_\_\_
congenital familial gingivostomatitis
29
White sponge nevus always involves the ?
cheek mucosa
30
Microscopically the white sponge nevus will have \_\_\_\_\_\_\_\_edema with broad fused _____ \_\_\_\_\_\_?
prickle cell rete pegs
31
Is White Sponge Nevus harmless or harmful?
harmless
32
What is a term for a white/gray layer of clear, thin, non wrinkled mucosa?
Leukodema
33
What lesion found in the mouth is USUALLY found on flexor surfaces of arms and legs?
Lichen Planus
34
The term for the raised white lines and dots (zig-zag "cracks") found in Lichen Planus?
Wicham Stria
35
Lichen Planus is due to?
over-correction of inflammatory response
36
Lichen Planus is seen microscopically with extensive _________ infiltration, liquefaction of \_\_\_\_\_\_\_\_, and a prominent ______ layer
lymphocyte basal layer granular
37
When you have Wicham Striae the lesion is called a ________ lichen planus
reticular
38
\_\_\_\_\_\_ Lichen Planus is characterized by painful, burning ulcer patches?
Erosive
39
What is the tx/fix for Lichen Planus?
No TX just let it run its course
40
Nicotine Stomatitis is found where?
palate
41
What is the etiology of Nicotine Stomatitis?
heat and tar irritant from smoking
42
Nicotine Stomatitis is sen clinically with _______ that have a central _______ corresponding to the inflamed \_\_\_\_\_\_\_?
papule red accessory saliva glands
43
Name this lesion that is caused by heat and irritants from smoking
Nicotine Stomatitis
44
This lesion is exacerbated by emotional stress and is seen microscopically with a prominent granular layer
Erosive Lichen Planus
45
This lesion is congenital and has a edematous prickle cell layer
White Sponge Nevus
46
This lesion is commonly found in the ala-traga zone (Skin flakes off then comes back flaky again)
Actinic Keratosis
47
What is this lesion called? What are the white "cracks" called?
Reticular Lichen Planus Wicham Striae
48
This lesion is often found on lower lip and predisposes to cancer
Solar Cheilosis
49
This type of white lesion is associated with malignancy and has dyskeratosis microscopically
Dysplastic Leukoplakia
50
This lesion is pre- ________ and has a \_\_\_\_\_% chance of progressing into a carcinoma
malignant 90
51
Is this normal? What is it called?
YES Cheek Bite (Morsicatio Buccarum)
52
What do we call a RED lesion when we dont know the cause?
Erythoplakia
53
There are currently ______ forms of Herpes?
8
54
What is the term for a FIRST encounter breakout of Herpes?
Primary Herpetic Gingivostomatitis
55
80% of the time is is herpes ___ or ___ when found in the oral cavity?
1 2
56
Which herpes simplex virus comes back more often?
2
57
What herpes virus causes Kaposi's sarcoma?
CMV Cytomegaly Virus
58
Epstein-Bar virus causes what common disease?
Infectious Mononucleosis
59
Recurrent Herpes lesions or commonly called _____ \_\_\_\_\_\_ are __ lesions that are found on the _____ gingiva?
Cold Sores, Fever Blisters etc. single attached
60
Where does the herpes virus live while dormant?
Trigeminal Ganglion
61
A cold sore lasts how long?
7-14 days
62
Herpes Zoster or _______ affects what age group?
Shingles 60 and over
63
Shingles is preceded by ______ and comes from the ______ region affecting the \_\_\_\_\_?
pain spinal trunk
64
What is the etiology of Shingles?
Vericella zoster (chicken pox)
65
What is the term for a canker sore?
Apthous ulcer
66
Canker sores appear on the _____ side of the mouth on the _______ gingiva?
wet unattached
67
What is the term for herpes under the nail bed?
Herpetic Whitlow
68
The etiology of a canker sore is ______ but probably due to?
unkown immune reaction to hemolytic strep
69
TB is a ______ associated disease?
lung
70
If TB affects the mouth it looks like an _____ or an ____ of the mucous membrane?
abcess ulcer
71
What is the tx for someone who gets TB?
INH therapy | (6 mo antibiotic therapy)
72
What is the pathognomonic for syphilis?
Spirochete-treponema pallidum
73
What accompanies the primary syphillis stage?
Big Chancre for 2-3 wks
74
The secondary stage of syphilis is affiliated with?
Flue-like symptoms with a mucous patch (weeks/months later)
75
What is the tertiary (3rd) stage of syphilis affiliated with?
Gumma (rubbery lesion in palate) Glossitis Death!!! (1-20 yrs later)
76
What is the most common fungal infection in the oral cavity?
Candidiasis
77
Oral Candidiasis is often called _______ and has a smooth, _____ or ____ plaque that \_\_\_\_\_be wiped off?
thrush white yellow can
78
What will the tissue look like if a yeat infection has been wiped away?
Red (on fire)
79
Older people who get thrush can present with?
Angular Cheilitis
80
What is the term for a common wart in the oral cavity?
Oral Verruca Vulgaris
81
What is a wart in the oral cavity caused by?
HPV
82
What age is the peak time to get a HPV vaccination?
11
83
What strains of HPV cause genital/oral warts?
6 And 11
84
What strains of HPV cause cervical cancer?
16, 18
85
Fordyce Granules are a _______ condition that presents as ectopic \_\_\_\_\_\_glands found in the _____ \_\_\_\_\_ of the mucosa?
normal sebaceous (oil) lamina propria
86
What is a raised, white irregular line on the buccal mucosa at occlusal plane level that CAN'T be wiped off?
Linea Alba
87
What is a white-grey film "saran-wrap" look to the buccal mucosa that CANT be wiped off?
Leukoedema
88
What are yellow creamy spots cound mostly in buccal mucosa with preponderance in males?
Fordyce Granules
89
What is the name for Cheek Biting?
Morsicatio Buccarum
90
What are two common causes of CHEMICAL burns of the mouth?
Bleach Asprin
91
Chemicals burn mucosa either through ____ or _____ reactions?
Systemic (allergic) local
92
What is an inherited disease resulting in clusters of capillaries with enlarged ends?
Hereditary Telangectasia
93

Pathophysiology (12 decks)

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