Unit I Med Review Flashcards Preview

Pharm > Unit I Med Review > Flashcards

Flashcards in Unit I Med Review Deck (50):
1

Trade name for Acetaminophen

Tylenol

2

Trade name for Ibuprofen

Motrin, Advil

3

Trade name for Celecoxib

Celebrex

4

Trade name for Oxycodone/APAP

Percocet

5

Trade name for Tramadol

Ultram

6

Trade name for Naloxone

Narcan

7

Trade name for Methotrexate

Rheumatrex, Trexall

8

Trade name for Hydroxychloroquine

Plaquenil

9

Trade name for Etenercept

Enbrel

10

Acetaminophen Category

Non-opioid analgesic

11

Acetaminophen Use

Mild-moderate pain; fever

12

Acetaminophen Dose

325-650mg PO q4-6hr
Max: 4000mg/day

13

Acetaminophen AE

Well tolerated; Hepatotoxicity, nephrotoxicity, anemia, blood dyscrasias, rare skin rxns, overdose->severe or fatal hepatotoxicity
CI: severe liver disease or hepatic impairment
Preg Cat: C

14

Ibuprofen Category

Nonselective NSAID

15

Ibuprofen Use

Mild-moderate pain

16

Ibuprofen Dose

200-400mg PO q4-6hr (Max: 3200mg/day)
400-800mg IV q6hr (Max: 3200mg/day)?

17

Ibuprofen AE

GI; renal; antiplatelet; CV; hepatic; CNS (sedation); skin (SJ/TEN)
CI: pts w/angioedema and bronchospasm w/ASA or other NSAID, severe hepatic impairment, CABG
Preg Cat: C; D > 30wks gestation

18

Celecoxib Category

Selective COX-2 Inhibitor

19

Celecoxib Use

Mild-moderate pain

20

Celecoxib Dose

OA: 100mg PO bid or 200mg PO qday
RA: 100-200mg PO big

21

Celecoxib AE

GI (< than N-NSAID); potential increased risk of CV events; renal; hepatic; CNS, skin [NO antiplatelet effect]
CI: sulfa allergy; ASA or NSAID allergy; 3rd trimester pregnancy, CABG
Preg Cat: C; D > 30wks gestation

22

Oxycodone/APAP Category

Opioid: u Agonist (related to Morphine)

23

Oxycodone/APAP Use

Moderate pain

24

Oxycodone/APAP Dose

5/325mg: 1-2 tabs PO q4-6hrs

25

Oxycodone/APAP AE

Drowsiness; nausea; vomiting; constipation; decreased respiratory rate; pruritus; tolerance; dependence; CYP3A4 substrate: BBW-toxicity
Preg Cat: C

26

Tramadol Category

Opoid: other opioid agonist

27

Tramadol Use

Moderate-Severe pain

28

Tramadol Dose

50-100mg PO q4-6hrs
Max: 400mg/day

29

Tramadol AE

Drowsiness; nausea; vomiting; constipation; decreased respiratory rate; pruritus; tolerance; dependence; Risk for dependence/addiction, seizures, death due to OD/suicide, CYP3A4 substrate
Preg Cat: C

30

Naloxone Category

Antidote; u Opioid Antagonist

31

Naloxone Use

Opoid OD; Reverse respiratory distress

32

Naloxone Dose

Resp Distress: 0.04-0.4mg IV (May Repeat q2-3min)
OD: 2mg IV

33

Naloxone AE

Related to reversing dependency and precipitating withdrawal: CV, CNS, GI, diaphoresis, hot flashes, shivering, yawning, etc
Preg Cat: C

34

Methotrexate Category

Non-Biologic DMARD

35

Methotrexate Use

RA: more active or severe

36

Methotrexate Dose

Oral: 7.5-20mg/week
Injectable: 7.5-20mg/wk
Monitor: LFTs and CBC q8wks

37

Methotrexate AE

Stomatitis; N/D; alopecia; increased LFTs; low liver toxicity risk; thrombocytopenia; leukopenia; rare pulmonary and lymphoproliferative toxicity.
Caffeine >180mg/day may decrease the effectiveness of MTX for RA
Drug Intx: PPI, NSAIDs, and ASA may decrease renal clearance
Toxicities: Myelosuppression, cirrhosis, hepatic fibrosis, pulmonary infiltrates or fibrosis
CI: liver disease, kidney impairment, lung disease, ETOH abuse, pregnancy and lactation
Preg Cat: X

38

Methotrexate Notes

Take w/Folic Acid 5mg/wk to decrease AE

39

Hydroxychloroquine Category

Non-Biologic DMARD

40

Hydroxychloroquine Use

Less active or milder RA

41

Hydroxychloroquine AE

Rash; diarrhea; abdominal cramps; infrequently increased risk renal toxicity if dose >6gm/kg
Toxicity: macular damage (periodic opthalmic exams to check)

42

Etenercept Category

Biologic DMARD (TNF Alpha Inhibitor)

43

Etanercept Use

RA

44

Etanercept AE

May exacerbate or cause CHF; increased risk of infections and lymphomas (Use caution in pts w/HF)

45

Hydroxychloroquine Notes

No monitoring required

46

Prednisone Category

Corticosteroid

47

Prednisone Use

RA, OA, MS pain

48

Prednisone Dose

RA: <7.5mg PO qday

49

Prednisone AE

Osteoporosis; HTN; hyperglycemia; cataracts; skin fragility; fluid retention; weight gain

50

Prednisone Notes

Take 1500mg elemental calcium per day and 400-800IU Vit D per day to prevent/decrease the risk of osteoporosis when taking Prednisone