Urinary Tract Infections Flashcards

(49 cards)

1
Q

What is the most common infectious disease in women?

A

Urinary tract infection (UTI)

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2
Q

What percentage of hospital-acquired infections are UTIs?

A

0.4

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3
Q

What are the three criteria to define a UTI?

A

Urinary symptoms, bacteriuria, and leukocyturia

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4
Q

How is significant bacteriuria defined?

A

> 1 x 10^5 CFU/mL

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5
Q

Which part of the urinary tract does pyelonephritis affect?

A

Renal parenchyma

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6
Q

What is the most common UTI classification by location?

A

Lower (bladder, urethra) and Upper (kidney)

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7
Q

What defines recurrent UTIs?

A

≥3 UTIs/year or ≥2 in 6 months

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8
Q

Who is at higher risk of complicated UTIs?

A

Men, pregnant women, menopausal women, anatomical abnormalities

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9
Q

What is asymptomatic bacteriuria?

A

Bacterial growth without symptoms

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10
Q

When should asymptomatic bacteriuria be treated?

A

Only in pregnancy

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11
Q

What is the main transmission route of UTIs?

A

Ascending route from urethra

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12
Q

Why are women more prone to UTIs?

A

Shorter urethra and proximity to anus

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13
Q

What factors prevent bacterial adhesion in the urinary tract?

A

Mucopolysaccharides and prostatic secretions

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14
Q

Which sexual behavior is a major risk factor for UTIs in women?

A

Sexual intercourse

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15
Q

What conditions favor bacterial growth in urine?

A

Diabetes and glucose in urine

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16
Q

What pathogen is responsible for 80% of UTIs?

A

Escherichia coli

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17
Q

What pathogens are linked to STDs and UTIs?

A

Chlamydia and Mycoplasma

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18
Q

What is the first-level diagnostic test for UTIs?

A

Urine test and culture

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19
Q

What imaging is used for complicated UTIs?

A

CT-IVU, ultrasound, or MRI

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20
Q

When is dynamic renal scintigraphy used?

A

In complicated or recurrent infections

21
Q

What must be done before prescribing antibiotics for UTIs?

22
Q

Which type of cystitis has no identifiable pathogen?

A

Abacterial cystitis

23
Q

What is a typical treatment for acute cystitis in women?

A

Single dose of fosfomycin

24
Q

What bacteria are most associated with pyelonephritis?

A

E. coli, Proteus, Klebsiella

25
What is a key sign of pyelonephritis?
Fever with flank pain and positive Giordano sign
26
What lab test helps identify pyelonephritis?
CRP, leukocytes, procalcitonin
27
What is the gold standard imaging for pyelonephritis?
CT-IVU
28
What is the first-line treatment for acute pyelonephritis?
IV antibiotics for 3-4 weeks
29
When is oral antibiotic sufficient in pyelonephritis?
For mild or non-obstructive cases
30
What is emphysematous pyelonephritis?
Gas-forming infection in diabetics
31
What sign on imaging indicates emphysematous pyelonephritis?
Bear-paw sign with gas in renal parenchyma
32
What are signs of complicated pyelonephritis?
Renal abscess, sepsis, or obstruction
33
What is the treatment for renal abscess?
IV antibiotics and possibly drainage
34
What can cause abacterial cystitis?
Chemotherapy, radiation, or parasites
35
What are protective urinary tract factors?
IgA, glycoproteins, and regular voiding
36
What symptom is common in cystitis?
Burning urination and urgency
37
What distinguishes complicated from uncomplicated UTI?
Presence of anatomical or functional abnormalities
38
What should be avoided in UTI to prevent resistance?
Unnecessary antibiotic treatment
39
What UTI treatment is adjusted in pregnancy?
Antibiotics are selected carefully to avoid fetal harm
40
What population sees increasing asymptomatic bacteriuria?
Elderly and catheterized patients
41
What are signs of urosepsis?
Fever, chills, shivering with urinary symptoms
42
What is the impact of menopause on UTIs?
Increased risk due to low estrogen
43
What is a contraindication in treating asymptomatic bacteriuria?
Treating non-pregnant women
44
What defines uncomplicated pyelonephritis?
Occurs in healthy individuals without obstruction
45
When is hospitalization needed for UTI?
Severe infection, high fever, or sepsis
46
How does biofilm affect UTI treatment?
Makes bacteria resistant and harder to detect
47
What is the role of post-void residual (PVR)?
To assess incomplete bladder emptying
48
Which agents are commonly used for IV UTI treatment?
Fluoroquinolones and ceftriaxone
49
What symptom can mimic cystitis in older women?
Bladder cancer presenting as hematuria