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From Flashcardlet > Uveitis: Bacterial Uveitis > Flashcards

Uveitis: Bacterial Uveitis Flashcards

0
Q

multifocal chorioretinitis, retinal vasculitis

A

main ocular findings in early congenital syphilis

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1
Q

interstitial keratitis, CN VIII deafness, Hutchinson teeth

A

Hutchinson triad

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2
Q

retinitis pigmentosa

A

a retinal variant of early congenital syphilis may mimic this disease

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3
Q

nonulcerative stromal keratitis with anterior uveitis

A

most common inflammatory sign of untreated late congenital syphilis

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4
Q

3 weeks

A

incubation period of syphilis after which the chancre appears

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5
Q

6-8 weeks

A

after appearance of the chancre, secondary syphilis arises after approximately this time period

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6
Q

10%, II

A

incidence of uveitis in the stage at which syphilis most commonly presents in the eye (two responses)

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7
Q

true

A

TRUE or FALSE: Uveitis can appear in ANY stage of syphilis

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8
Q

focal or multifocal chorioretinitis

A

most common posterior segment manifestation of syphilis

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9
Q

posterior placoid chorioretinitis with early hypofluorescence and late staining

A

pathognomonic picture of posterior segment syphilis (though not most common)

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10
Q

focal retinal vasculitis

A

this form of ocular syphilis may masquerade as a BRVO

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11
Q

ARN, PORN

A

syphilis may mimic these viral retinal inflammations though with a much slower course (and a good response to penicillin!)

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12
Q

both

A

histological type of inflammation in syphilis: granulomatous, nongranulomatous or both

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13
Q

roseola, vascularized papules, vasularized nodules, gummata

A

four findings in iris involvement in syphilis

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14
Q

optic neuritis, neuroretinitis

A

two presentations of syphilis that are more common in HIV/AIDS patients

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15
Q

secondary syphilis

A

when do the treponemal antibodies become positive in patients with syphilis?

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16
Q

IgM FTA-ABS

A

confirmatory test for congenital syphilis

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17
Q

leptospirosis, leprosy, malaria, SLE, RA, advanced age

A

false-positive treponemal tests can be seen in these conditionis (three infectious, two inflammatory, one other)

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18
Q

HIV

A

patients with this condition have an increase in both false-positive and false-negative testing rates for syphilis

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19
Q

CSF VDRL

A

most specfic diagnostic test for neurosyphilis (should be performed in any patient with syphilitic uveitis)

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20
Q

CSF FTA-ABS

A

most sensitive diagnostic test for neurosyphilis

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21
Q

none

A

alternative treatment for patients with neurosyphilis

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22
Q

10-14 days

A

duration of therapy for neurosyphilis

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23
Q

daily IM procaine penicillin

A

alternative to IV penicillin G for neurosyphilis

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24
Q

Ixodes pacificus

A

vector for Borrelia burgdorferi on the west coast

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25
Q

JIA

A

major differential item for Lyme disease in children

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26
Q

25%

A

in endemic areas, as many as this percentage of new cases of CN VII palsy are attributable to Lyme disease

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27
Q

5 months

A

onset of stage 3 Lyme disease after initial infection

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28
Q

HLA-DR2, HLA-DR4

A

haplotypes associated with poor response to antibiotics in Lyme disease

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29
Q

acrodermatitis chronica atrophicans

A

term for bluish red lesion on the extremities that may progress to fibrous bands and nodules in stage 3 Lyme disease

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30
Q

follicular conjunctivitis, episcleritis

A

most common ocular manifestation of stage 1 Lyme disease (seen in 11%); second answer = this is less commonly seen

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31
Q

intermediate uveitis

A

one of the most common intraocular manifestations of Lyme disease (usually stage 2, occasionally stage 3)

32
Q

peripheral multifocal choroiditis

A

distinctive posterior segment finding in some cases of Lyme disease

33
Q

keratitis

A

most common ocular manifestation of stage 3 Lyme disease

34
Q

HIV

A

the CDC recommendation for diagnosis of Lyme disease resembles the traditional means of diagnosing this other infection

35
Q

LP

A

In both syphilis and Lyme disease, identification in intraocular disease warrants this test

36
Q

8

A

age at which doxycycline can be given in Lyme disease

37
Q

Babesiosis, Erlichiosis

A

two common coinfections in Lyme disease

38
Q

Hawaii

A

About half of the 100 to 200 cases of leptospirosis annually are diagnosed in this state

39
Q

severe systemic leptospirosis

A

circumcorneal conjunctival congestion on the third to fourth day of illness is considered pathognomonic for this entity

40
Q

leptospiruria, meningitis, uveitis

A

three most important manifestations of the immune phase of leptospirosis

41
Q

acute, severe panuveitis

A

most common form of uveitis in leptospirosis

42
Q

false

A

TRUE or FALSE: The prognosis of leptospiral uveitis is generally quite poor

43
Q

doxycycline

A

systemic treatment of choice for leptospirosis

44
Q

tuberculosis

A

the most important systemic infectious disease worldwide

45
Q

20%

A

percentage of patients with extrapulmonary TB, percentage of patients with TB who test negative on skin testing (same for both)

46
Q

10%

A

percentage of patients infected with TB who develop symptomatic disease

47
Q

false

A

TRUE or FALSE: Isolated granulomatous anterior uveitis without posterior segment involvement is relatively common

48
Q

scleritis, phlyctenulosis, interstitial keratitis

A

three surface ocular manifestations of tuberculosis

49
Q

TB

A

this bacterial cause of anterior uveitis usually follows a chronic waxing and waning course with posterior synechiae and uveitic glaucoma commonly supervening

50
Q

disseminated choroiditis

A

most common posterior segment manifestation of tuberculosis

51
Q

choroidal tubercle

A

may be one of the earliest signs of miliary TB, especially in an immunocompromised host

52
Q

HIV/AIDS

A

In this setting, tuberculous uveitis often progresses despite appropriate therapy

53
Q

macular star

A

a large choroidal tubercle in the posterior pole may be accompanied by this finding

54
Q

false

A

TRUE or FALSE: A positive QuantiFERON Gold TB test indicates active infection, in contrast to PPD (Mantoux) skin testing

55
Q

diabetes, renal failure

A

Systemic conditions that put a patient in the 10 mm threshold group for PPD testing

56
Q

BCG, atypical mycobacteria, intraluminal BCG for bladder cancer

A

three causes of false positive TB testing

57
Q

purified cord factor

A

antibodies against this TB antigen are now available to diagnose active pulmonary infection

58
Q

inflammatory

A

Apart from direct extension from the choroid, tuberculosis involvement in the retina is primarily by this mechanism

59
Q

direct observed care

A

the standard of care in treatment of tuberculosis (treatment strategy)

60
Q

3 weeks

A

how long before starting anti-TNF therapy in a patient with latent TB should isoniazid prophylaxis be started

61
Q

serpiginous choroiditis

A

tuberculosis involvement in the retina can often resemble this white-dot syndrome

62
Q

bacillary angiomatosis, cat scratch disease, Parinaud oculoglandular syndrome, Leber idiopathic stellate neuroretinitis

A

four diseases for which Bartonella henselae has been implicated

63
Q

fall and winter, southern US

A

seasonal and geographic trend in Bartonella henselae infection

64
Q

sporotrichosis

A

cat scratch disease most resembles this in its presentation

65
Q

5-10%

A

incidence of ocular involvement in CSD

66
Q

sudden, unilateral

A

nature of vision loss in neuroretinitis: gradual or sudden, unilateral or bilateral

67
Q

false

A

TRUE or FALSE: Any level of positive titer for B. henselae is considered positive in the proper clinical context

68
Q

doxycycline

A

the antibiotic usually given for CSD

69
Q

migratory arthritis

A

most common symptom in Whipple disease (80%)

70
Q

5%

A

prevalence of intraocular involvement in Whipple disease (less than…)

71
Q

bilateral panuveitis, retinal vasculitis

A

two basic features of Whipple disease uveitis

72
Q

TMP-SMX

A

preferred treatment of Whipple disease

73
Q

duodenal biopsy

A

gold standard of diagnosis for Whipple disease

74
Q

P. aeruginosa

A

most common cause of infectious scleritis following pterygium excision

75
Q

VZV, HSV

A

two major causes of chronic infectious scleritis

76
Q

lamellar scleral biopsy

A

should be considered if a case of scleritis fails to respond to anti-inflammatory therapy

77
Q

surgery, trauma

A

scleritis should be presumed infectious in these two contexts

78
Q

intermediate

A

This anatomical type of uveitis is distinctly uncommon in syphilis

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