Uveitis: Clinical Approach Flashcards

0
Q

anterior, intermediate, posterior, panuveitis

A

four classifications of uveitis by anatomical classification according to the SUN working group

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1
Q

the middle, pigmented, vascular structures of the eye

A

describe the uvea

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2
Q

acute, insidious

A

two descriptors for uveitis onset according to the SUN working group

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3
Q

limited, persistent

A

two descriptors for uveitis duration according to the SUN working group

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4
Q

acute, recurrent, chronic

A

three descriptors for uveitis course according to the SUN working group

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5
Q

inactive, worsening activity, improved activity, remission

A

four descriptors for uveitis activity according to the SUN working group

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6
Q

CME, cataracts

A

two main causes of vision loss in intermediate uveitis

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7
Q

idiopathic, Behcet disease, seronegative spondyloarthopathies, infectious endophthalmitis

A

differential (4) for acute, sudden-onset, severe anterior uveitis

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8
Q

HLA-B27

A

only test that may need to be obtained in an idiopathic acute, sudden-onset anterior uveitis

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9
Q

HLA-B27, sacroiliac films

A

two tests that need to be obtained with suspected seronegative spondyloarthropathy-associated anterior uveitis

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10
Q

true

A

TRUE or FALSE: HLA testing is rarely done to confirm Behcet’s disease

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11
Q

sarcoidosis, traumatic, glaucomatocyclitic crisis, herpetic, syphilis, low-grade endophthalmitis, IOL-related iritis, idiopathic

A

differential (7) for moderate-severity anterior uveitis

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12
Q

syphilis

A

must be considered in a steroid-unresponsive anterior uveitis

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13
Q

glaucomacyclitic crisis, herpetic

A

anterior uveitis (2) with increased IOP

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14
Q

lysozyme, ACE, CXR

A

three screening tests for sarcoidosis

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15
Q

biopsy

A

confirmatory test in sarcoidosis

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16
Q

JIA-related iridocyclitis, Fuchs heterochromatic iridocyclitis, low-grade endophthalmitis, idiopathic

A

differential (4) for chronic anterior uveitis

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17
Q

sarcoidosis, Lyme disease, multiple sclerosis, intraocular lymphoma, pars planitis

A

differential (5) for intermediate uveitis

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18
Q

ELISA

A

test to be performed if lyme-related uveitis is suspected

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19
Q

vitrectomy, cytology

A

may need to be performed (2) for intermediate uveitis in a patient over 50

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20
Q

toxoplasmosis (prominent), toxocariasis, CMV retinitis (not prominent)

A

differential for focal chorioretinitis WITH vitritis (3)

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21
Q

geophagia

A

in a case of suspected toxocariasis, ask about this behavior

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22
Q

ELISA

A

tests for toxocara and toxoplasma

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23
Q

true

A

TRUE or FALSE: Acute anterior iritis usually implies a sudden onset.

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24
Q

metastasis

A

Of concern in a focal chorioretinitis WITHOUT vitritis.

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25
Q

white dot syndromes, OHS

A

Two items on differential for multifocal chorioretinitis WITHOUT vitritis

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26
Q

onchocerciasis

A

Of concern in a diffuse chorioretinitis WITHOUT vitritis

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27
Q

true

A

TRUE or FALSE: A clinical appearance of granulomatous uveitis often does not correlate with pathological findings

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28
Q

lymphocyte

A

the predominant inflammatory cell of uveitis

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29
Q

false

A

TRUE or FALSE: Pigment dispersion is not a sign of anterior uveitis

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30
Q

nodules, vitiligo

A

two eyelid signs seen in uveitis

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31
Q

nodules, ciliary flush, diffuse injection

A

three conjunctival signs in uveitis

32
Q

fibrin, keratic precipitates, pigment, band keratopathy

A

four corneal signs in uveitis

33
Q

cell, flare, pigment

A

three AC/PC signs in uveitis

34
Q

posterior synechiae, atrophy, heterochromia, miosis, nodules

A

five iris signs in uveitis

35
Q

inflammatory cells, traction bands

A

two vitreous signs in uveitis

36
Q

snowbanking

A

pars plana sign in uveitis

37
Q

inflammatory cells, blood vessel cuffing, edema, CME, RPE changes, ERM

A

six retinal findings in uveitis

38
Q

choroidal infiltrate, atrophy, neovascularization

A

three choroidal findings in uveitis

39
Q

edema, neovascularization

A

two optic nerve findings in uveitis

40
Q

1x1 mm, 45

A

dimensions and angle of parallelipiped in checking for cell and flare

41
Q

1-5

A

number of cells in 0.5+ cell

42
Q

16-25

A

number of cells in 2+ cell

43
Q

> 50

A

number of cells in 4+ cell

44
Q

1-2

A

grading of flare if iris details clear

45
Q

3+

A

flare grading: iris details hazy

46
Q

4+

A

fibrinous or plasmoid AC are synonymous with this grade of flare

47
Q

purulent

A

term for AC reaction with leukocytes and hypopyon

48
Q

sanguinoid

A

term for AC reaction with leukocytes, erythrocytes, and hypopyon mixed with hyphema

49
Q

Koeppe nodules

A

iris nodules at the pupillary border

50
Q

Busacca nodules

A

iris nodules at the midpupil

51
Q

Berlin nodules

A

iris nodules at the angle

52
Q

1-10

A

number of vitreous cells in 0.5+ cell

53
Q

21-30

A

number of vitreous cells in 2+ cell

54
Q

> 100

A

number of vitreous cells in 4+ cell

55
Q

trauma, travel, eating habits, pets, sexual habits, drug use

A

basic historical elements that should be explored in a uveitis workup

56
Q

naming-meshing system

A

system used to match a patient’s presentation with a known uveitic entity

57
Q

10%

A

percentage of all blindness in the US that can be attributed to uveitis

58
Q

15 in 100,000

A

incidence of uveitis in the US

59
Q

sarcoidosis, Behcet disease

A

two most common causes of uveitis in Japan

60
Q

birdshot retinochoroiditis

A

type of uveitis seen particularly in western Europe

61
Q

tuberculosis, leptospirosis

A

two leading causes of infectious uveitis in India

62
Q

anterior-panuveitis-posterior-intermediate

A

list the anatomical types of uveitis by prevalence

63
Q

tuberculosis, syphilis, sarcoidosis

A

three diseases that most uveitis specialists will rule out when the history is not suggestive

64
Q

type 1 hypofluorescence

A

ICG pattern of early and late multifocal areas of hypofluorescence (inflammation of the choriocapillaris)

65
Q

MEWDS

A

main cause of type 1 hypofluorescence on ICG

66
Q

type 2 hypofluorescence

A

ICG pattern of early hypofluorescence and late hyperfluorescence (inflammation of the choroidal stroma)

67
Q

VKH syndrome, sympathetic ophthalmia, birdshot retinochoroidopathy, sarcoidosis, APMPPE, serpiginous

A

major diseases with type 2 choroidal hypofluorescence

68
Q

birdshot retinochoroiditis

A

ERG (cone flicker implicit time) is useful to follow this uveitic entitiy

69
Q

cytology

A

should be obtained from a paracentesis specimen of a sanguinoid AC reaction

70
Q

0.1-0.2 mL

A

amount of fluid that is usually withdrawn in an AC tap

71
Q

infliximab

A

this anti-inflammatory is contraindicated in patients with MS

72
Q

cyclophosphamide-bladder cancer, chlorambucil-leukemia

A

two major systemic alkylating agents and the neoplasms associated with them

73
Q

toxoplasmosis, Fuchs heterochromatic iridocyclitis, herpes, CMV

A

uveitis entities associated with diffuse stellate KPs

74
Q

aggressive hydration

A

practical suggestion to a person taking cyclophosphamide

75
Q

POHS, PIC, punctate outer retinal toxoplasmosis, SSPE, serpiginous

A

posterior uveitis entities for which vitreous cell is very uncommon

76
Q

Behcet syndrome, SO, VKH, necrotizing sclerouveitis

A

uveitis entities for which early immunomodulating therapy is classically beneficial

77
Q

30 months

A

treatment duration of Retisert (fluocinolone) implant

78
Q

metipranolol, bisphosphonates

A

only two medications that fulfill all the criteria for truly causing uveitis