UWorld_7.25

Question 1

Secondary causes of gout

Answer 1

• hematologic malignancies
• tumor lysis syndrome
• psoriasis

Question 2

Sx of polycythemia vera

Answer 2

• H/A
• aquagenic pruritus
• HSM

Question 3

Ventilation =

Answer 3

TV * RR

Question 4

Heart defects assoc. w/Digeorge

Answer 4

• cyanotic heart defects:
• truncus art.
• transposition

Question 5

Cause of death in FA

Answer 5

cardiomyopathy

Question 6

Gonococcal septic arthritis presentation

Answer 6

• asymmetric polyarthralgias or isolate purulent mono/oligo arthralgias
• assoc. w/skin rash and tenosynovitis
• young, sexually active
• most silent (no preceding infection)

Question 7

Reactive arthritis presentation

Answer 7

• assoc. w/chlamydia or GI infections
• arthritis
• conjunctivitis
• urethritis

Question 8

Vaccines in chronic liver disease

Answer 8

• Hep A/Hep B
• flu
• Tdap q10 yrs.
• PCV23 followed by normal pneumococcoal @ 65

Question 9

Dx of myasthenia gravis

Answer 9

• edrophonium (tensilon) test
• ice pack test ==> improvement in weakness
• Ach receptor antibodies
• CT for thymoma eval

Question 10

Enuresis age cut-off and tx

Answer 10

• incontinence > 5yo

- 1st line = desmopressin; 2nd line: TCAs (impramine, amitriptyline)

Question 11

Sodium bicarb use in metabolic acidosis

Answer 11

@ pH

Question 12

isoniazid SE

Answer 12

• pyridoxine (B6) antagonist

- supplement w/B6 during tx

Question 13

Sideroblastic anemia presentation

Answer 13

-microcytic/hypochromic + elevated iron and decreased TIBC

Question 14

elevated alk phos + anti-mitochondrial ab + ==> dx?

Answer 14

primary biliary cholangitis

Question 15

Tx of primary biliary cholangitis

Answer 15

ursodeoxycholic acid

Question 16

Neuro status in clinical brain death

Answer 16

• absent cortical and brain stem fxns

- spinal cord may be fxning, DTRs present

Question 17

Legg-Calve-Perthes disease

Answer 17

• idiopathic avascular necrosis of femoral capital epiphysis

- boys ages 4-10

Question 18

Tx of cryptococcal meningoencephalitis

Answer 18

• amphotericin B + flucytosine IV x 2wks
• then fluconazole x 1 yr.
• serial LPs to reduce ICP if needed

Question 19

cryptococcal meningoencephalitis presentation

Answer 19

• subacute fungal infection

- HIV w/CD4

Question 20

Statin MOA

Answer 20

• imhibit HMG-CoA reductase

- inhibits intracellular synthesis of LDL receptors ==> decreased receptors @ cell membranes

Question 21

Imaging in eval of aortic dissection

Answer 21

• TEE if elevated Cr or contrast allergy
• chest CT
• MRI

Question 22

Trimethoprim SE

Answer 22

• hyperkalemia 2/2 blockade of epithelial sodium channel @ collecting tubule
• inhibits renal tubular secretion of Cr ==> artificial elevation of Cr

Question 23

Cat bite ppx

Answer 23

amoxicillin/clavulanate

Question 24

Adenosine use

Answer 24

• management of patients w/narrow-QRS-complex tachycardia

- slows conduction through AV node

Question 25

Paroxysmal supraventricular tachycardia presentation

Answer 25

- abrupt onset/offset - AVNRT, AVRT, atrial tachy, jxnl tachy - palpitations, dizziness, lightheadedness - SOB, diaphoresis, chest pain, presyncope

Question 26

Electrolytes in Cushing's

Answer 26

hypernatremia | hypokalemia

Question 27

Dx of esophageal perforation

Answer 27

- CXR - CT - water-soluble esophagogram

Question 28

Testing if idiopathic thrombocytopenic purpura

Answer 28

HIV and Hep C