vasculidities

Question 1

what are the large vessel vasculitides

Answer 1

giant cell arteritis, takayasu’s arteritis

Question 2

what are the medium sized vessel ones

Answer 2

polyarteritis nodosa, kawasaki, thromboangiitis obliterans

Question 3

small vessel vasculitides

Answer 3

GPA, MPA, churg-strauss, HSP

Question 4

GIant cell: who? where? presentation?

Answer 4

older ppl. extracranial (temporal arteries). Fever, headache, polymyalgia rheumatica (girdle muscle pain). Ophthalmic artery

Question 5

takayasu’s: who? aka? what arteries?

Answer 5

younger asian women. pulseless dz. aorta and subclavian

Question 6

treatment for most vasculitides

Answer 6

steroids, cyclophosphamide

Question 7

Polyarteritis nodosa: triad, viral association

Answer 7

mononeuritis multiplex (weakness of random points), hematuria, cutaneous. Hep B associated

Question 8

Kawasaki: pentad, treatment

Answer 8

fever, conjunctivitis, strawberry tongue, cervical lymphadenopathy, desquamative rash. ASA, IVIG

Question 9

Thromboangiitis obliterans: who? associated with?

Answer 9

young smoking males. Raynaud’s phenom

Question 10

Henoch-schonlein purpura: who? what deposits?

Answer 10

young kids; IgA (esp in kidney); abdominal pain.

Question 11

P anca reacts with what? C anca?

Answer 11

MPO; PR3

Question 12

Granulomatosis with polyangiitis: two hallmarks? anca? triad of involvement?

Answer 12

granulomas, necrosis of small vessels. C-anca. Upper and lower RT, renal.

Question 13

Microscopic polyangiitis: what organs are involved. Anca?

Answer 13

lung and kidney, p-anca

Question 14

churg-strauss: triad? other associate disorders?

Answer 14

asthma, allergic rhinitis, nasal polyps. Mononeuritis multiplex. can have purpura, myocarditis