Virus Lecture 20 Flashcards Preview

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Flashcards in Virus Lecture 20 Deck (32):
1

What DNA virus has reverse transcriptase?

Hepadnaviridae

2

Retro

Reverse/backward reflects the property of retroviruses to use their RNA genome to produce DNA intermediates using reverse transcriptase, an RNA-dependant DNA polymerase

3

What was the first retrovirus described?

Equine infectious anemia

4

What is unique about the retrovirus genome?

Diploid (pseudodiploid), consisting of a dimer of two molecules of linear positive-sense, single-stranded RNA

5

The linear DNA forms integrate into cellular chromosomal DNA as a?

Provirus

6

Oncogenic retrovirus is?

A retrovirus with the gene that has the potential to cause cancer.

7

How is equine infectious anemia transmitted?

Mechanically transmitted through stable fly

8

What does equine infectious anemia infect.

Infects monocytes and macrophages

9

Name the retrovirus in cats?

Feline immunodeficiency virus

10

How is feline immunodeficiency virus transmitted?

Through bite injuries

11

What does feline immunodeficiency virus infect?

Depletion of CD4 positive T helper cells

12

What RNA virus is enveloped, bullet shaped, helically coiled, and nucleocapsid?

Rhabdoviridae

13

What is the genus for Rhabdoviridae?

Lyssavirus

14

What virus is rabies virus?

Rhabdoviridae

15

To diagnose rabies what is looked for?

Infected neurons contain intracytoplasmic inclusion bodies called Negri bodies.

16

What animals get rabies? (according to our teacher)

Dogs, cats, wild canid and felids, vampire bats, mongoose

17

What virus is pleomorphic or filamentous?

Filoviridae: Ebolavirus

18

What is the progression of disease with Filoviridae: Ebolavirus?

Monocyte infection > release of cytokines>endothelial injury>haemorrhage

19

What virus has genomes composed of several (6-8) segemnts of single- stranded RNA?

Orthomyxoviridae

20

What does Orthomyxoviridae cause?

Influenza and Glycoprotein spikes
H=Hemagglutinin (HA)
N=Neuraminidase (NA)

21

For Orthomyxoviridae what is the difference between antigenic shift and antigenic drift?

Antigenic shift is a reassortment of segments of genes
Antigenic drift is a mutation of genes.

22

The Picornaviridae causes what disease in animals and what disease in humans?

Animals: Aphthovirus (foot and mouth)
Humans: Enterovirus (human poliovirus)

23

Which virus is enveloped with spikes called peplomeres?

Coronaviridae

24

What disease are caused by Coronaviridae in cats and humans?

Cats: Feline enteric coronavirus (feline infectious peritonitis virus)
Humans: SARS (Sever acute respiratory syndrome)

25

What virus causes West Nile virus?

Flaviviridae, flavivirus

26

What are the two virus that are arthropod borne?

Flaviviridae and Swine Pox

27

What is the genus name for bovine viral diarrhea virus and classic swine fever in the family Flaviviridae?

Pestivirus

28

Who are dead end hosts for arthropod borne virus?

Humans and horses

29

T:F Bovine viral diarrhea virus is a laten infection.

False
Bovine viral diarrhea virus is a persistent infection.

30

What disease are caused by Togaviridae?

Alphavirus
Eastern equine encephalitis virus
Western equine encephalitis virus
Highlands J virus
Venezuelan equine encephalitis virus

31

What is an arbovirus?

Arthropod borne virus, replicates and transmitted by arthropods

32

What virus causes canine distemper?

Paramyxoviridae