W04_02 Hyperkinetic movement disorders Flashcards Preview

Brain and Behaviour > W04_02 Hyperkinetic movement disorders > Flashcards

Flashcards in W04_02 Hyperkinetic movement disorders Deck (11):
1

definition of dystonia

abnormal sustained posture of a body part due to involuntary muscle activation of both agonists and antagonists

2

most common genetic classes of dystonia?

DYTs

3

name common DYT dystonias

DYT1 - early onset
DYT5 - DOPA responsive
DYT11 - myoclonus dystonia

4

wilson's disease is a mutation in this gene on this chromosome

ATP7B gene on chromosome 13

5

name some symptoms of acute dystonic reaction

torticollis, stridor, opisthotonus, retrocollis

6

which 3 kinds of drugs to give for acute dystonic reactions?

benztropine,
diphenhydramine
amantadine

7

drug treatments for dystonia?

artane,
baclofen,
tetrabenazine,
l-dopa,
surgery/dbs in GPi

8

drug treatments for tics?

clonidine,
neuroleptics,
tetrabenzine

9

difference between chorea and akathisia?

chorea - don't know.
akathisia - urge to move.

10

slow writing distal limbs is called?

athetosis

11

features of huntington's?

slowed/hypometric saccades;
chorea progressing to parkinsonism;
silted gait