Flashcards in L11 CSF Dynamics and BBB Deck (13)
how much does the brain weigh?
1400 g in air.
45 g intracranially
how often is the CSF turned over per day?
3x per day
which kind of cells line the ventricles?
name the two components of the BBB
blood-interstitial fluid barrier
blood-cerebrospinal fluid barrier
what causes cerebral endothelial cells to form tight junctions and no fenestrations?
astrocytic foot processes.
note: fenestrations exist in choroid plexus.
the blood-CSF barrier is formed by which structure?
which kinds of ependymal cells have tight junctions?
choroidal ependymal cells have tight junctions
how does the CSF leave the ventricles?
lateral aperture x2
total volume of CSF?
mostly in subarachnoid space
rate of production of CSF?
500 mL / day
two means of returning CSF to vasculature?
along sheaths of cranial/spinal nerves into lymph system (especially olfactory tract)
name for condition when CSF movement is blocked