L11 CSF Dynamics and BBB Flashcards Preview

Brain and Behaviour > L11 CSF Dynamics and BBB > Flashcards

Flashcards in L11 CSF Dynamics and BBB Deck (13):
1

how much does the brain weigh?

1400 g in air.
45 g intracranially

2

how often is the CSF turned over per day?

3x per day

3

which kind of cells line the ventricles?

ependymal cells.

4

name the two components of the BBB

blood-interstitial fluid barrier
blood-cerebrospinal fluid barrier

5

what causes cerebral endothelial cells to form tight junctions and no fenestrations?

astrocytic foot processes.
note: fenestrations exist in choroid plexus.

6

the blood-CSF barrier is formed by which structure?

choroid plexus

7

which kinds of ependymal cells have tight junctions?

choroidal ependymal cells have tight junctions

8

how does the CSF leave the ventricles?

median aperture
lateral aperture x2

9

total volume of CSF?

140 mL;
mostly in subarachnoid space

10

rate of production of CSF?

500 mL / day

11

two means of returning CSF to vasculature?

arachnoid granulations
along sheaths of cranial/spinal nerves into lymph system (especially olfactory tract)

12

name for condition when CSF movement is blocked

obstructive hydrocephalus

13

name for condition when CSF absorption is blocked

communicating hydrocephalus