Week 6 part 2 Flashcards Preview

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Flashcards in Week 6 part 2 Deck (26):
1

Commonest uterine mass?

Fibroids

2

what is siad to have occured to a uterine fibroid if pain is disproportionate e.g. in pregnancy and menopause?

Red degeneration

3

What invesgitations are done for suspected fibroids?

Haemoglobin if heavy bleeding
Ultrasound - smooth echogenic mass
MRI for precise location

4

Fibroid treatment?

Traditionally hysterectomy if family complete

5

Give to examples of functional ovarian cysts related to ovulation?

1. Follicular cyst
2. Luteal cyst

6

What cysts are typically associated with severe dysmenorrhaoea and premenstrual pain, also dyspareunia and often associated with subfertility?

Endometriotic cysts

7

Give an example of a benign cystic teratoma (arising from germ cell, primary ovarian tumour)?

Dermoid cyst

8

What is Meigs syndrome?

Triad of benign ovarian tumour (fibroma) with ascites and pleural effusion

9

What might malignant germ cell tumorus of ovary produce?

HCG or AFP

10

BRACA1 & 2?

Breast and ovarian cancer

11

HNPCC

Lynch syndrome - colorectal cancer, endometrial cancer, ovarian cancer

12

What is protective factor for ovarian cancer?

OCP

13

Ovarain cancer tumour marker?

CA 125 - RAISED in 80% of cancer
Carcino-embryonic antigen CEA

14

What can endometriosis, peritonitis, pregnancy, pancreatitis, ascites all cause a moderate elevation in??

CA-125

15

What ovarian tumours cause a particular rise in carcino embryonic antigen CEA? Mian function of CEA is to exclude mets from GI primary

mUcinous tumours

16

How do you calculate RMI for ovarian cancer?

Menopausal status x serum CA125 x US score

17

What biochemistry test should be requested when investigating ovarian canceR?

Serum albumin

18

ascites/ bloating
pelvic mass/ bladder dysfunction
pleural effusion/shortness of breath

Ovarian cancer

19

Patient with an RMI above what should be referred to hospital?

Above 200

20

FIGO staging of ovarian cancer: confined to 1 or both ovaries

I

21

FIGO staging of ovarian cancer: spread beyond pelkvis within the abdomen?

III

22

FIGO staging of ovarian cancer: Spread to other pelvic organs e.g. uterus, fallopian tube

II

23

FIGO staging of ovarian cancer: spread into other organs e.g. liver, lungs?

iv

24

What should all women with high grade early stage Ia-Ib ovarian cancer ben considered for?

Chemotherapy

25

For advanced disease ovarian cancer what is drug of choice for both single and combnation therapy?

Carboplatin (platinum drug)

26

What are the most common extra-abdominal cancers that cause malignant bowel obstruction?

Breast
Melanoma
Lung