Flashcards in Week 6 part 2 Deck (26):
Commonest uterine mass?
what is siad to have occured to a uterine fibroid if pain is disproportionate e.g. in pregnancy and menopause?
What invesgitations are done for suspected fibroids?
Haemoglobin if heavy bleeding
Ultrasound - smooth echogenic mass
MRI for precise location
Traditionally hysterectomy if family complete
Give to examples of functional ovarian cysts related to ovulation?
1. Follicular cyst
2. Luteal cyst
What cysts are typically associated with severe dysmenorrhaoea and premenstrual pain, also dyspareunia and often associated with subfertility?
Give an example of a benign cystic teratoma (arising from germ cell, primary ovarian tumour)?
What is Meigs syndrome?
Triad of benign ovarian tumour (fibroma) with ascites and pleural effusion
What might malignant germ cell tumorus of ovary produce?
HCG or AFP
BRACA1 & 2?
Breast and ovarian cancer
Lynch syndrome - colorectal cancer, endometrial cancer, ovarian cancer
What is protective factor for ovarian cancer?
Ovarain cancer tumour marker?
CA 125 - RAISED in 80% of cancer
Carcino-embryonic antigen CEA
What can endometriosis, peritonitis, pregnancy, pancreatitis, ascites all cause a moderate elevation in??
What ovarian tumours cause a particular rise in carcino embryonic antigen CEA? Mian function of CEA is to exclude mets from GI primary
How do you calculate RMI for ovarian cancer?
Menopausal status x serum CA125 x US score
What biochemistry test should be requested when investigating ovarian canceR?
pelvic mass/ bladder dysfunction
pleural effusion/shortness of breath
Patient with an RMI above what should be referred to hospital?
FIGO staging of ovarian cancer: confined to 1 or both ovaries
FIGO staging of ovarian cancer: spread beyond pelkvis within the abdomen?
FIGO staging of ovarian cancer: Spread to other pelvic organs e.g. uterus, fallopian tube
FIGO staging of ovarian cancer: spread into other organs e.g. liver, lungs?
What should all women with high grade early stage Ia-Ib ovarian cancer ben considered for?
For advanced disease ovarian cancer what is drug of choice for both single and combnation therapy?
Carboplatin (platinum drug)