1. Nucleic Acid Structure and Chemistry Flashcards Preview

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Flashcards in 1. Nucleic Acid Structure and Chemistry Deck (13)
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1

Difference between nucleoside and nucleotide

Nucleoside = sugar + base

Nucleotide = sugar + base + 5' phosphate(s)

2

Word for 'between different nucleic acid strains'

INTER-molecular

3

Bond that links adjacent nucleotides together at 5' C

Phosphodiester

4

Bond that links the deoxyribose moiety to the base at C1'

Glycosidic

5

What type of bond holds 2 complementary strands of DNA together?

Hydrogen

6

Loss of secondary structure (reversible)

Denaturation

7

Acid conditions promote hydrolysis of these 2 bonds resulting in loss of primary DNA structure

- Glycosidic
- Phosphodiester

8

What occurs at C1' of a deoxynucleotide

Glycosidic linkage with base

9

Linkage found between 5' and 3' carbons of adjacent nucleotides of the same strand

Phosphodiester

10

Loss of primary structure

Degradation

11

Word for 'within the same nucleic acid strand'

INTRA-molecular

12

How do DNA nucleases destroy primary DNA structure

By hydrolyzing phosphodiester linakges between adjacent deoxyribose sugars

13

Difference between C2' position of DNA vs RNA

DNA - H
RNA - OH