Flashcards in 1. Nucleic Acid Structure and Chemistry Deck (13)
Difference between nucleoside and nucleotide
Nucleoside = sugar + base
Nucleotide = sugar + base + 5' phosphate(s)
Word for 'between different nucleic acid strains'
Bond that links adjacent nucleotides together at 5' C
Bond that links the deoxyribose moiety to the base at C1'
What type of bond holds 2 complementary strands of DNA together?
Loss of secondary structure (reversible)
Acid conditions promote hydrolysis of these 2 bonds resulting in loss of primary DNA structure
What occurs at C1' of a deoxynucleotide
Glycosidic linkage with base
Linkage found between 5' and 3' carbons of adjacent nucleotides of the same strand
Loss of primary structure
Word for 'within the same nucleic acid strand'
How do DNA nucleases destroy primary DNA structure
By hydrolyzing phosphodiester linakges between adjacent deoxyribose sugars