10 Minute topic HIV Flashcards Preview

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Flashcards in 10 Minute topic HIV Deck (18):
1

Stages of HIV

Stage 1: Primary HIV infection
Stage 2: Chronic asymptomatic infection
Stage 3: AIDS

2

Stage 1: Primary HIV infection

manifestations occur in 2-4 weeks
Flu-like sx
rapid rise in viral load (increased CD8, decreased CD4+ cells)

3

Stage 2: chronic asymptomatic infection

may be asymptomatic for 10+ years
client makes anti-HIV antibodies
Viral load increases
Loss of immunity begins

4

Stage 3: AIDS

life threatening opportunistic infections
Client needs to remain up to date with vaccines including flu

5

Populations at risk for HIV

women due to mucous membranes in the vagina
post menopausal women have dry and thin mucous membranes in the vagina

6

Stage 1 diagnostics

no defining conditions
CD4, T lymphocyte count is 500 cells/mm3 or more

7

Stage 2 diagnostics

CD4, T lymphocyte count is between 200 and 499

8

Stage 3 diagnostics

CD4, T lymphocyte count is less than 200

9

CBC and differential with HIV

shows anemia, thrombocytopenia and leukopenia

10

Platelets with HIV

<150,000 (low)

11

HAART therapy (Highly active antiretroviral therapy)

involves using three to four HIV medications in combination with other antiretroviral medications to reduce medication resistance, adverse effects, and dosages

12

HAART drug categories

Entry/ infusion inhibitors
NRTI's (Nucleoside reverse transcriptase inhibitors)
NNRTIs (Non-nucleoside reverse transcriptase inhibitors)
Protease inhibitors
Antineoplastic medication

13

Entry/ infusion inhibitors

helps decrease of virus and limit spread
Enfuvirtide (Fuzeon)
given SQ,

14

NRTI's (Nucleoside reverse transcriptase inhibitors)

Zidovudine (Retrovir)
Interferes with the virus’s ability to convert RNA into DNA

15

NNRTIs (Non-nucleoside reverse transcriptase inhibitors)

Delvirdine (Rescriptor) and efavirenz (Sustiva)
Inhibit viral replication in cells

16

Protease inhibitors

Amprenavir (agenerase), nefinavir (Viracept) saquinavir (Invirase), and indinavir (Crixivan)
Inhibit an enzyme needed for the virus to replicate

17

Antineoplastic medication

Interleukin (Interferon)
immunostimulant that enhances the immune response and reduces the production of cancer cells (used commonly with Kaposi’s sarcoma)

18

HIV associated malignancies

Kaposi’s sarcoma, lymphoma, and squamous cell carcinoma