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Microbiology > Meningoencephalitis > Flashcards

Meningoencephalitis Flashcards

1
Q

What are the two prions for Meningoencephalitis?

A

Primary Amoebic and Granulomatous Amoebic

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2
Q

What is the causative organism for Primary Amoebic Meningoencephalitis?

A

Naegleria fowleri

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3
Q

What are the most common modes of transmission for Naegleria fowleri (Primary Amoebic Meningoencephalitis)?

A

Vehicle (exposure while swimming in water)

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4
Q

What are the virulence factors for Naegleria fowleri (Primary Amoebic Meningoencephalitis)?

A

Invasiveness

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5
Q

How do you culture/diagnose Naegleria foweri (Primary Amoebic Meningoencephalitis)?

A

Examination of CSF, brain imaging, biopsy

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6
Q

How do you prevent (Primary Amoebic Meningoencephalitis) Naegleria foweri infection?

A

Limit warm freshwater or untreated tap water entering nasal passages

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7
Q

How do you treat (Primary Amoebic Meningoencephalitis) Naegleria foweleri infection?

A

Pentamidine, sulfadiazine

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8
Q

What are the epidemiological features for Naegleria fowleri (Primary Amoebic Meningoencephalitis)?

A

United States: 0-7 cases a year; 97% case-fatality rate; spreading to northern states as climate warms.

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9
Q

What is the causative agent of Granulomatous Amoebic Meningoencephalitis?

A

Acanthamoeba

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10
Q

What are the most common modes of transmission for Acanthamoeba (Granulomatous Amoebic Meningoencephalitis)?

A

Direct contact

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11
Q

What are the virulence factors of Acanthamoeba (Granulomatous Amoebic Meningoencphalitis)?

A

Invasiveness

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12
Q

How do you culture/diagnose Acanthamoeba (Granulomatous Amoebic Meningoencephalitis)?

A

Examination of CSF; brain imaging, biopsy

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13
Q

How do you prevent Acanthamoeba infection (Granulomatous Amoebic Meningoecephalitis)?

A
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14
Q

How do you treat (Granulomatous Amoebic Meningoencephalitis) Acanthamoeba infection?

A

Surgical excision of granulomas; pentamidine

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15
Q

What are the epidemiological features of Acanthamoeba (Granulomatous Amoebic Meningoencephalitis)?

A

Predominantly occurs in immunocompromised patients

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Microbiology (47 decks)

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