Chagas Disease Flashcards

1
Q

What is the causative organism for Chagas Disease?

A

Trypanosoma cruzi (Prion)

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2
Q

What are the most common modes of transmission for Chagas Disease (Trypanosoma cruzi)?

A

Biological vector (triatomine bug), vertical

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3
Q

What are the virulence factors for Chagas Disease (Trypansoma cruzi)?

A

Antioxidant enzymes, co-opting host antigens; induces autoimmunity

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4
Q

How do you culture/diagnose Chagas Disease (Trypanosoma cruzi)?

A

Blood smear in acute phase; serological methods in later stages

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5
Q

How do you prevent Chagas Disease (Trypanosoma cruzi)?

A

Insect control

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6
Q

How do you treat Chagas Disease (Trypanosoma cruzi)?

A

Consult CDC

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7
Q

What are the epidemiological features of Chagas Disease (Trypansoma cruzi)?

A

Endemic in Central and South America; 300,000 cases present in United States; considered a neglected parasitic infection (NPI) (see Insight 22.2)

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