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Microbiology > Blood and Tissue Protozoa - T. cruzii > Flashcards

Blood and Tissue Protozoa - T. cruzii Flashcards

1
Q

Blood and tissue protozoan

All 4 forms (APET)

AMASTIGOTE
PROMASTIGOTE
EPIMASTIGOTE
TRYPOMASTIGOTE

A

Trypanosoma cruzii

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2
Q

Transmission of T. cruzii

A

FECES of REDUVIID BUG (kissing bug, triatoma, cone nose or assassin bug) deposited in a PAINLESS bite

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3
Q

Infective stage of T. cruzii

A

Metacyclic trypomastigote (epimastigote)

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4
Q

Diagnostic stage of T. cruzii

A

Trypomastigote

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5
Q

Most frequently and severely affected tissue

A

CARDIAC MUSCLES (myocytes)

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6
Q

CHAGAS DISEASE/AMERICAN TRYPANOSOMIASIS

A

ACUTE PHASE

  • facial edema
  • nodule, CHAGOMA
  • fever, lymphadenopathy, hepatosplenomegaly
  • ROMANA SIGN

CHRONIC FORM

  • MYOCARDITIS, dilated cardiomyopathy w/ apical atrophy
  • MEGACOLON, MEGAESOPHAGUS (2nd achalasia)
  • death - usually d.t. cardiac arrhythmias or CHF
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7
Q

subcutaneous inflammatory nodule

A

CHAGOMA

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8
Q

unilateral palpebral swelling

A

ROMANA’S SIGN

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9
Q

Treatment of Chagas Disease

A

ACUTE

  • Nifurtimox
  • Benznidazole
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Microbiology (106 decks)

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