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Microbiology > Intestinal and Tissue Nematodes - TRICHINELLA SPIRALIS > Flashcards

Intestinal and Tissue Nematodes - TRICHINELLA SPIRALIS Flashcards

1
Q

Tissue nematode

PIGS - intermediate host

the ONLY INTRACELLULAR helminths

A

Trichinella spiralis

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2
Q

Transmission of Trichinella spiralis

A

digesting undercooked pork

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3
Q

Diagnostic test for Trichinella spiralis

A

MUSCLE BIOPSY: most definitive; LARVAE W/N STRIATED MUSCLE

elevated CPKs

xenodiagnosis

Bentonite Flocculation Test

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4
Q

Pathogenesis of Trichinella spiralis

A

INTESTINAL STAGE: liberated from pork by gastric juices

MUSCLE STAGE: disseminated HEMATOGENOUSLY to STRIATED SKELETAL MUSCLE – encysted w/n a host derived cell (NURSE CELL)

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5
Q

MILD DISEASE

A

fever, muscle pain (MYALGIA)

PERIORBITAL EDEMA

eosinophilia

SUBCONJUNCTIVAL HEMORRHAGE - hemorrhagic phemomena

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6
Q

SEVERE DISEASE

A

myocarditis
encephalitis
pneumonia
RESPIRATORY MYOSITIS

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7
Q

Treatment for trichinosis

A

Thiabendazole

EARLY INFECTION
*Mebendazole

SEVERE INFECTION
*steroids + Albendazole

NO EFFECTIVE TREATMENT

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