Tu - Role of medical imaging in personalized medicine

Question 1

Name 3 benefits for using personalized medicine.

Answer 1

Improved patient safety, increased effectiveness and cost efficiency of treatment, more cost effective development of drugs.

Question 2

In which ways does personalized medicine lead to improved patient safety?

Answer 2

Preventing mis dosing, less adverse reactions

Question 3

What is the EU definition of personalized medicine?

Answer 3

Providing the right treatment, to the right patient at the right dose, at the right time.

Question 4

What is the definition of personalized medicine according to the National Cancer Institute?

Answer 4

A form of medicine that uses info about a person’s genes, proteins, and environment to prevent, diagnose and treat disease.

Question 5

What are risk biomarkers used for in personalized medicine?

Answer 5

Predicting the risk of developing a disease

Question 6

What are diagnostic biomarkers used for in personalized medicine?

Answer 6

Diagnosing a specific disease as early as possible

Question 7

What are prognostic biomarkers used for in personalized medicine?

Answer 7

Following the evolution (Aggressiveness) of a disease

Question 8

What are therapeutic biomarkers used for in personalized medicine?

Answer 8

Testing drug targets

Question 9

What are predictive biomarkers used for in personalized medicine?

Answer 9

Predicting the response of toxicity of a treatment

Question 10

What are surrogate biomarkers used for in personalized medicine?

Answer 10

After starting therapy, they indicate whether at the end the therapy will be effective

Question 11

What is ME medicine?

Answer 11

Medicine that is personalized

Question 12

What is WE medicine?

Answer 12

Medicine for everyone in the population ie. Vaccines

Question 13

Name 2 negatives for ME medicine.

Answer 13

Some forms of molecular medicine are largely unproven and sometimes harmful.
Expensive medicine can be bad for other patients.

Question 14

Name 2 negatives for WE medicine

Answer 14

Austerity cuts & public distrust

Question 15

What is a companion diagnostic? (explain complicated)

Answer 15

Companion diagnostic is an in vitro diagnostic device or an imaging tool that defines a subset of patients responding particularly well to a therapeutic drug, aids in risk/benefit assessment, and is a prerequisite (=indicator) for receiving the drug

Question 16

How does aducanumab get across the blood brain barrier?

Answer 16

A shuttle bound to aducanumab binds to a transferring BBB receptor and brings aducanumab across the BBB