Mo - Oncolytic viruses and immune modulation of the tumor microenvironment Flashcards
1
Q
What is a neoantigen?
A
Antigens in the tumors that derive from mutations in the DNA. It is seen as an antigen that has never been seen before by the immune system.
2
Q
Why is it important for GSK3B to be active?
A
Because then you get less immature dendritic cells and more T cells to fight the tumor
3
Q
In which form (unphosphorylated/phosphorylated) is GSK3B active?
A
Unphosphorylated
