Leukocytes Flashcards
-penia suffix
Decreased concentration
-cytosis or philia
Increased concentration
How many granulocyte pools are the the blood marrow
3
Proliferative, maturation, storage
Pools in the blood
Circulating pool
Marinating pool
Species with more leukocyte in the marginating pool than in the circulating pool
Cats
What pool are you drawing from when you take blood
Circulating blood
What pool in the bone marrow is largest
Maturation pool
What species has a small granulocyte reserve (storage pool)
Ruminants
Neutrophil transit time in marrow
7-10days
Neutrophil circulation half life
6-10hrs
Left shift
Increase in immature neutrophils in blood
Why does a left shift occur
Stimulation of more immature cells to be released due to neutrophils leaving the blood to go to the tissue. Now more need to enter from the storage pool in order to allow for neutrophils to be in the blood. Once those are all used up, you start releasing the band cells into the peripheral blood
Regenerative left shift
Expected response where bone marrow is able to keep up. There are more segmented cells than non-segmented. Orderly release of neutrophils. Leukocytosis due to neutrophilia
Degenerative left shift
Bone marrow is not keeping up with demand. Non segmented cells outnumber the segmented cells.
What is the hallmark of acute inflammation
Band neutrophils (lack definitive indentation in neutrophil nucleus)
