Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PSYC2360 > 6: PSYCHOPHARMACOLOGY > Flashcards

6: PSYCHOPHARMACOLOGY Flashcards

1
Q

2 TYPES OF RECEPTORS

A
  1. IONOTROPIC RECEPTORS (DIRECT METHOD)
  2. METABOTROPIC RECEPTORS (INDIRECT METHOD)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

study of effects of drugs on nervous system + bhvr

A

PSYCHOPHARMACOLOGY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

changes a drug produces in animal’s physiological processes/bhvr

A

DRUG EFFECTS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

chemical substance that effects/alters cell function in v small quantities

A

DRUG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

locations at which drugs interact w cells of the body thus affecting some biochemical processes of these cells

A

SITES OF ACTION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

2 BASIC CLASSIFICATIONS OF DRUG ACTIONS

A
  1. AGONIST
  2. ANTAGONIST
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

drug that FACILITATES effects of a particular NT on postsynaptic cell

A

AGONIST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

drug that INHIBITS effects of a particular NT on postsynaptic cell

A

ANTAGONIST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
  1. serves as PRECURSOR to NT
  2. stimulates RELEASE of NT
  3. receptor BINDING (same as if NT = opening channels)
  4. BLOCKS auto receptors (INCR synth/release NT)
  5. inhibition of REUPTAKE
  6. inhibition of DEACTIVATION
A

6 WAYS DRUGS CAN AGONIZE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
  1. prevents synthesis of NT
  2. blocks RELEASE of NT
  3. receptor BLOCKER (NTs not allowed to bind to receptors)
  4. STIMULATES autoreceptors (INHIBITS synth/release of NT)
  5. prevents storage of NT in vesicle
A

5 WAYS DRUGS CAN ANTAGONIZE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

binds at SAME site NT would

A

DRUG ACTION OF DIRECT (COMPETITIVE) AGONIST/ANTAGONIST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

binds at DIFF site than NT would

A

DRUG ACTION OF INDIRECT (NON-COMPETITIVE) AGONIST/ANTAGONIST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

class of AMINES that includes CATECHOLAMINES + INDOLAMINES

A

MONOAMINES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

example of QUARTERNARY AMINE

A

ACETYLCHOLINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

4 MAJOR NT SYSTEMS

A
  1. ACETYLCHOLINE
  2. DOPAMINE
  3. NOREPINEPHRINE
  4. SEROTONIN
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

precursor of DOPAMINE that = used to treat PARKINSON’S bc it is a DOPAMINE AGONIST (INCR DOPAMINE levels)

A

L-DOPA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

neurological disease characterized by tremors/rigidity of limbs/poor balance/difficulty initiating mvmts

A

PARKINSON’S DISEASE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

PARKINSON’S DISEASE = caused by degeneration of that _____ system

A

NIGROSTRIATAL SYSTEM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

drugs that alter DOPAMINE uptake + produce SCHIZO-like delusions

A

AMPHETAMINES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

units used for protein synthesis by all cells of brain

A

AMINO ACIDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

2 AMINO ACID NTS THAT ACCOMPLISH MOST SYNAPTIC COMMUNICATION

A
  1. GLUTAMATE
  2. GABA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

primary EXCITATORY AA NT

A

GLUTAMATE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

primary INHIBITORY AA NT

A

GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

effects of GLUTAMATE + GABA in which info learned + remembered = transmitted by neurons secreting these NTS

A

INFO-TRANSMITTING EFFECTS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q
  1. DORSOLATERAL PONS
  2. BASAL FOREBRAIN
  3. MESOCORTICAL SYSTEM
A

3 NEURAL PATHWAYS OF ACETYLCHOLINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q
  1. NIGROSTRIATAL SYSTEM
  2. MESOLIMBIC SYSTEM
  3. MESOCORTICAL SYSTEM
A

3 NEURAL PATHWAYS OF DOPAMINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

NEURAL PATHWAY OF NOREPINEPHRINE

A

LOCUS COERULEUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

NEURAL PATHWAY OF SEROTONIN

A

RAPHE NUCLEI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q
  • learning
  • memory
  • sleep
A

ACETYLCHOLINE CNS FUNCTIONS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q
  • muscle contraction
A

ACETYLCHOLINE PNS FUNCTION

31
Q

DECR in ACETYLCHOLINE = ___ DISEASE

A

ALZHEIMER’S

32
Q
  • voluntary mvmt
  • attn
  • learning
  • reinforcement of abused drugs
  • planning
  • prob solving
A

DOPAMINE CNS FUNCTIONS

33
Q

DECR in DOPAMINE = ___ DISEASE

A

PARKINSON’S

34
Q

INCR in DOPAMINE = ___ DISEASE

A

SCHIZOPHRENIA

35
Q
  • vigilance
  • attn
  • sexual bhvr
  • appetite
A

NOREPINEPHRINE CNS FUNCTIONS

36
Q
  • ANS regulation (regulate heart rate/BP)
A

NOREPINEPHRINE PNS FUNCTION

37
Q

DECR in NOREPINEPHRINE = ___

A

DEPRESSION

38
Q

INCR in NOREPINEPHRINE = ___

A

MANIA

39
Q
  • mood regulation
  • eating
  • sleep
  • dreaming
  • arousal
  • impulse control
A

SEROTONIN CNS FUNCTIONS

40
Q
  • ENTERIC NERVOUS SYSTEM functions (digestion)
A

SEROTONIN PNS FUNCTION

41
Q

DECR in SEROTONIN = ___

A

DEPRESSION

42
Q

INCR in SEROTONIN = ___/___/___

A

OCD/TICS/SCHIZOPHRENIA

43
Q

where GLUTAMATE + GABA = STORED

A

in the VESICLES

44
Q
  1. NMDA RECEPTOR
  2. AMPA RECEPTOR
  3. KAINATE RECEPTOR
  4. METABOTROPIC GLUTAMATE RECEPTOR
A

4 MAJOR TYPES OF GLUTAMATE RECEPTORS

45
Q

specialized IONOTROPIC GLUTAMATE receptor that controls CALCIUM channel normally blocked by Mg2+ ions

A

NMDA RECEPTOR

46
Q

(most common) IONOTROPIC GLUTAMATE receptor that controls SODIUM channel that produces EPSPs when open

A

AMPA RECEPTOR

47
Q

proteins that move GLUTAMATE from synapse

A

EXCITATORY AMINO ACID TRANSPORTERS

48
Q

IONOTROPIC GABA receptors that control CHLORIDE channels

A

GABA A RECEPTORS

49
Q

consist of 2+ AMINO ACIDS linked together by PEPTIDE BONDS

A

PEPTIDES

50
Q

drugs used for centuries to relieve PAIN

A

OPIATES

51
Q

class of peptides secreted by brain that act as OPIATES

A

ENDOGENEOUS OPIOIDS

52
Q

EXAMPLES OF ENDOGENOUS OPIOIDS

A
  • OPIUM
  • MORPHINE
  • HEROIN
  • OXYCODONE
53
Q

ENDOGENEOUS OPIOIDS = ___ for OPIATE receptors

A

AGONISTS

54
Q

idea that WANTING = equivalent to CRAVING a drug + LIKING = PLEASURE from drug-taking

A

INCENTIVE SENSITIZATION MODEL (WANTING + LIKING MODEL)

55
Q

idea that FAST-acting drugs = MOST addictive + SLOW-acting drugs = addictive bc of MEMORY assoc w taking the drug

A

POSITIVE REINFORCEMENT

56
Q

EXAMPLES OF FAST-ACTING DRUGS

A

COCAINE/HEROIN

57
Q

EXAMPLE OF SLOW-ACTING DRUG

A

ALCOHOL

58
Q

brain location where addictive drugs/other reinforcers release DOPAMINE

A

NUCLEUS ACCUMBENS

59
Q

ANTAGONIST at DOPAMINE transporters that causes them to run in REVERSE which releases NT into synapse + blocks reuptake of NTs

A

AMPHETAMINE/METHAMPHETMINE

60
Q

AGONIST that INCR effects of DOPAMINE

A

DOPAMINE AGONIST

61
Q

thing that lets DOPAMINE react in synapse for LONGER period of time

A

REUPTAKE INHIBITOR

62
Q

drug that INHIBITS reuptake of DOPAMINE

A

COCAIN/METHYLPHENIDATE

63
Q

serious mental disorder characterized by POSITIVE/NEGATIVE symptoms (hallucinations/lack of emotion)

A

SCHIZOPHRENIA

64
Q

2 TYPES OF SYMPTOMS OF SCHIZOPHRENIA

A
  1. POSITIVE
  2. NEGATIVE
65
Q
  • hallucinations
  • delusions
  • paranoia
A

POSITIVE SYMPTOMS OF SCHIZO

66
Q
  • lack of emotion/energy/directedness
A

NEGATIVE SYMPTOMS OF SCHIZO

67
Q

OVERACTIVITY of MESOLIMBIC DOPAMINE pathway mediates POSITIVE symptoms of SCHIZO + UNDERACTIVITY of MESOLIMBIC DOPAMINE pathway mediates NEGATIVE symptoms of SCHIZO

A

DOPAMINE THEORY OF SCHIZOPHRENIA

68
Q

degenerative brain disorder of unknown origin that causes:
- progressive memory loss
-motor deficits
- death

A

ALZHEIMERS

69
Q

4 BRAIN ABNORMALITIES ASSOC W ALZHEIMERS

A
  1. NUCLEUS BASALIS deteriorates
  2. NEUROFIBRILLARY TANGLES
  3. AMYLOID PLAQUES
  4. cell loss from NUCLEUS BASALIS OF MEYNERY
70
Q

dying neuron containing important stuff that formerly served as cell’s internal skeleton

A

NEUROFIBRILLARY TANGLES

71
Q

extracellular deposit containing a core of AMYLOID

A

AMYLOID PLAQUES

72
Q

first cells to be affected in ALZHEIMERS DISEASE

A

CHOLINERGIC NEURONS IN BASAL FOREBRAIN

73
Q

2 TREATMENTS FOR ALZHEIMERS

A
  1. COGNITIVE ENHANCERS
  2. NMDA RECEPTOR ANTAGONISTS

PSYC2360 (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions