Pagets Disease of the Bone

Question 1

what is pagets disease of the bone

Answer 1

idiopathic disease which disrupts normal bone renewal cycle
excessive osteoclast activity and bone tissue replaced with abnormal weak tissue

Question 2

risk factors for pagets disease of the bone

Answer 2

older age (>50)
M>F
European descent

Question 3

presentation of pagets disease of the bone

Answer 3

bone pain
stiffness
bowing of long bones
may be asymptomatic sometimes

Question 4

what laboratory findings would you expect to find in pagets disease of the bone

Answer 4

normal Ca, normal PTH, raised ALP

Question 5

management of pagets disease of the bone

Answer 5

analgesia for bone pain
calcitonin and alendronate
patient education: gentle exercise, falls risk assessment