Hypothyroidism

Question 1

what is the normal function of the thyroid hormone

Answer 1

increases cardiac output
ventillation rate
basal metabolic rate
increases sympathetic activity
and catabolism

Question 2

what are general symptoms of Hypothyroidism

Answer 2

weight gain, constipation
fatigue, depression, memory loss
bradycardia
hypertension
dry skin, malar rash, hair loss
fluid retention - oedema, pleural effusion, ascites
amenorrhoea
intolerance to the cold

Question 3

what are some causes of Hypothyroidism

Answer 3

Hashimoto’s thyroiditis
iodine deficiency
lithium and amiodarone
treatment of hyperthyroidism
secondary - hypopituitarism

Question 4

describe Hashimoto’s thyroiditis

Answer 4

most common cause in developed world
autoimmune inflammation of the thyroid
genetic and environment factors contribute
may have goitre before atrophy

Question 5

which antibodies are associated with Hashimoto’s

Answer 5

anti thyroid peroxidase (anti-TPO)
anti thyroglobulin antibodies

Question 6

management of Hypothyroidism

Answer 6

levothyroxine
titrate till normal TSH
monthly monitoring till TSH is stable