7-SYSTEMIC FUNGI Flashcards

1
Q

MOT:

A

inhalation of spores (mold)

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2
Q

Specimen:

A

Sputum

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3
Q

contains HEPA filter

A

BSL III=BSC class II

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4
Q

No

A

person-to-person contact

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5
Q

Colonies:

A

cottony white to brown

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6
Q

blastomycosis/Gilchrist disease

A

Blastomyces dermatitidis

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7
Q

chronic granulomatous and suppurative infection of the lungs, skin and mucous membranes

A

Blastomyces dermatitidis

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8
Q

Primary Lung

A

Blastomyces dermatitidis

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9
Q

Chronic skin-bone

A

Blastomyces dermatitidis

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10
Q

Slow to moderate growers

A

Blastomyces dermatitidis

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11
Q

Rapid growers (3 to 4 days)

A

Blastomyces dermatitidis

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12
Q

Dipmorphic

A

Coccidioides immitis

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13
Q

habitat: soil

A

Coccidioides immitis

Paracoccidioides brasiliensis

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14
Q

habitat: alkaline soil

A

Histoplasma capsulatum

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15
Q

coccidioidomycosis/Valley fever

A

Coccidioides immitis

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16
Q

Asymptomatic pulmonary disease

A

Coccidioides immitis

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17
Q

skin infections are characterized by erythema nodosum and multiforme and arthritis

A

Coccidioides immitis

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18
Q

Symptomatic: fever, respiratory distress, cough, anorexia, headache, malaise, and myalgias

A

Coccidioides immitis

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19
Q

most virulent human mycosis

A

Coccidioides immitis

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20
Q

histoplasmosis

A

Histoplasma capsulatum

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21
Q

coin lesions, flattened lesions in lungs

A

Histoplasma capsulatum

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22
Q

very fatal and may lead to death to immunodeficient/ immunosuppressed patient

A

Histoplasma capsulatum

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23
Q

Acquired in bird poops, bat guanos/ bat poops

A

Histoplasma capsulatum

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24
Q

“Cave’s disease”

A

Histoplasma capsulatum

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25
Q

Specimen: blood, urine, CSF

A

Histoplasma capsulatum

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26
Q

Paracoccidiodomycosis

A

Paracoccidioides brasiliensis

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27
Q

South American blastomycosis

A

Paracoccidioides brasiliensis

28
Q

Brazilian blastomycosis

A

Paracoccidioides brasiliensis

29
Q

Lutz-Splendore-Almeida disease

A

Paracoccidioides brasiliensis

30
Q

paracoccidioidal granuloma

A

Paracoccidioides brasiliensis

31
Q

lung infection

A

Paracoccidioides brasiliensis

32
Q

asymptomatic and self- limiting

A

Paracoccidioides brasiliensis

33
Q

spelunker’s disease

A

Histoplasma capsulatum

34
Q

Darling’s disease (pulmonary disease)

A

Histoplasma capsulatum

35
Q

cave disease

A

Histoplasma capsulatum

36
Q

reticuloendothelial cytomycosis

A

Histoplasma capsulatum

37
Q

not common

A

Paracoccidioides brasiliensis

38
Q

Endemic in Mississippi and Ohio river valleys

A

Blastomyces dermatitidis

39
Q

Endemic in Southwest United States (Mexico), Central and South America

A

Coccidioides immitis

40
Q

Endemic in Ohio, Missouri, Mississippi river valleys

A

Histoplasma capsulatum

41
Q

Endemic in Central and South America

A

Paracoccidioides brasiliensis

42
Q

Culture Media: Blood agar

A

Blastomyces dermatitidis

43
Q

White to dark tan; young colonies tenacious, older colonies glabrous to woolly

A

Blastomyces dermatitidis

44
Q

Culture: 22oC

A

Coccidioides immitis

45
Q

White to tan to dark gray

A

Coccidioides immitis

46
Q

Young colonies tenacious, older colonies cottony

A

Coccidioides immitis

47
Q

Culture: pines medium, glucose-cysteine blood, or BHI with blood agar

A

Histoplasma capsulatum

48
Q

White to brownish mold

A

Histoplasma capsulatum

49
Q

Woolly, cottony, or granular

A

Histoplasma capsulatum

50
Q

BHI with blood agar- confirmatory test for Histoplasma capsulatum (grow under 37oC)

A

Histoplasma capsulatum

51
Q

Wright’s-Giemsa for capsule

A

Histoplasma capsulatum

52
Q

White to beige; colony glabrous, leathery, flat to wrinkled, folded, or velvety

A

Paracoccidioides brasiliensis

53
Q

Hyphae: fine hyaline septate hyphae

A

Blastomyces dermatitidis

54
Q

Conidia: lollipop in appearance, borne directly from the hyphae or on conidiophores

A

Blastomyces dermatitidis

55
Q

Yeast: large yeast (8-12 um) o resembles the figure 8

A

Blastomyces dermatitidis

56
Q

Daughter cell is attached by broad necks

A

Blastomyces dermatitidis

57
Q

Hyphae: septate hyaline with varying widths

A

Coccidioides immitis

58
Q

Conidia: arthroconidia (barrel shaped)

A

Coccidioides immitis

59
Q

Tissue form: spherules (30-60 um) containing endospore

A

Coccidioides immitis

60
Q

Hyphae: very fine septate hyaline hyphae

A

Histoplasma capsulatum

61
Q

Macroconidia: sunflower in bloom; large unicellular, spherical with tuberculate walls

A

Histoplasma capsulatum

62
Q

Microconidia: borne directly or in short conidiophores

A

Histoplasma capsulatum

63
Q

Yeast form: blastoconidia with narrow necks

A

Histoplasma capsulatum

64
Q

Hyphae: same with Coccidiodes

A

Paracoccidioides brasiliensis

65
Q

Conidia: not common

A

Paracoccidioides brasiliensis

66
Q

Yeast: mariner’s wheel

A

Paracoccidioides brasiliensis