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MYCOLOGY AND VIROLOGY > FLAVIVIRIDAE, RHABDOVIRIDAE, TOGAVIRIDAE > Flashcards

FLAVIVIRIDAE, RHABDOVIRIDAE, TOGAVIRIDAE Flashcards

1
Q

Break-bone fever

A

Dengue Fever Virus

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2
Q

● Enveloped and icosahedral with a single stranded ,positive sense RNA genome

A

ZIKA VIRUS

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3
Q

ZIKA VIRUS

● First Isolated from (?) in the Zika Forest of Uganda

A

Rhesus Macaque

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4
Q

● Positive sense single stranded RNA virus

A

WEST NILE VIRUS

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5
Q

● This can cause Encephalitis

A

WEST NILE VIRUS

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6
Q

WEST NILE VIRUS

● First discovered in the ―West Nile ― province of Uganda in

A

1937

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7
Q

● A single-stranded

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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8
Q

● RNA virus, enveloped

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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9
Q

● Bites of infected mosquito

A

Yellow Fever Virus

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10
Q

Yellow Fever Virus 3 Types of transmission cycle

A

● Sylvatic (or jungle) yellow fever
● Intermediate yellow fever
● Urban yellow fever

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11
Q

Bite of an infected Aedes species (Ae. aegypti or Ae. albopictus) mosquito

A

Dengue Fever ViruS

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12
Q

Mosquito ( Aedes aegypti and Aedes albopictus)

A

Dengue Fever Viru

ZIKA VIRUS

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13
Q

● Vertical Transmission

A

ZIKA VIRUS

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14
Q

● Blood Transfusion

A

ZIKA VIRUS

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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15
Q

MOT
● Birds
● Mosquito

A

WEST NILE VIRUS

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16
Q

Bite of infected Culex species mosquitoes; Vector Mosquito

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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17
Q

Nucleic acid amplification test

A

Dengue Fever Viru

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18
Q

Serologic tests

A

Dengue Fever Viru

WEST NILE VIRUS

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19
Q

RT-PCR

A

ZIKA VIRUS

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20
Q

Enzyme-linked immunosorbent assay (ELISA) test

A

DF

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

HEP C

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21
Q

Polymerase chain reaction (PCR)

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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22
Q

Vaccine

A

Flavi

Arbo

Yellow Fever Virus

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23
Q

Use insect repellent

A

Dengue Fever Virus

ZIKA VIRUS

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24
Q

● Wear loose-fitting long sleeved shirts and long pants

A

Dengue Fever Viru

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25
Q

● Control mosquitoes inside and outside your home

A

Dengue Fever Viru

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26
Q

Vector control

A

ZIKA VIRUS

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27
Q

● Avoid unprotected sex

A

ZIKA VIRUS

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28
Q

● Use insect repellent

A

Dengue Fever Virus

ZIKA VIRUS

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29
Q

No vaccine (SLE)

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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30
Q

Inactivated Vero cell culture

A
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31
Q

derived Japanese encephalitis vaccine manufactured by IXIARO (Japanese Encephalitis)

A

Inactivated Vero cell culture

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32
Q

only JE vaccine licensed and available in the United States

A

Inactivated Vero cell culture

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33
Q

Inactivated Vero cell culture

● it was approved in March 2009 for use in people aged

A

17 years and older

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34
Q

Inactivated Vero cell culture

● May 2013 : it was approved for use in children (?)

A

2 months through 16 years of age

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35
Q

● Fever headache, Muscle aches, Nausea, Red eyes, face, tongue, Yellow skin and eyes.

A

Yellow Fever Virus

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36
Q

● Fever, severe headache, nausea, pain behind the eyes muscle and joint pains.

A

Dengue Fever Viru

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37
Q

● Incubation: 4–10 days after infection; last for 2–7 days

A

Dengue Fever Virus

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38
Q

Asymptomatic

A

ZIKA VIRUS

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39
Q

● Incubation: 2-14 day

A

ZIKA VIRUS

WEST NILE VIRUS

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40
Q

● Symptoms occur in 20%-40% of infected people

A

WEST NILE VIRUS

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41
Q

● Incubation: 2-14 day

A

ZIKA VIRUS

WEST NILE VIRUS

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42
Q

● blood-brain barrier: lymphocytic meningitis

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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43
Q

● fever, headache, nausea, vomiting, diarrhea, and myalgias

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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44
Q

● altered mental status, agitation, confusion, and coma.

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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45
Q

● Incubation: 5 to 15 days

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

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46
Q

● Blood transfusion, intravenous drug abuse, hemodialysis, sexual contact with infected partners, acupuncture, tattooing, and sharing of razors

A
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47
Q

Screening Antibody Test HCV

A

anti-HCV EIA, and RTPCR

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48
Q

is used to quantify virus in the blood to monitor antiviral therapy.

A

RT-PCR and quantitative bDNA (branched chain DNA)

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49
Q

used to detect acute hepatitis C infection

A

ELISA

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50
Q

used to determine chronic hepatitis C disease

A

PCR

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51
Q

are used to differentiate patients who are likely to respond to therapy from those with lower response rates.

A

Highly Sensitive Molecular Biopsy

52
Q

is used to identify genotypes more or less likely to respond to therapy

A

HCV Genotyping

53
Q

Enveloped virus with a single-stranded RNA genome

A

Vesicular Stomatitis Virus

54
Q

● Bullet shaped or Rod shaped

A

Vesicular Stomatitis Virus

55
Q

● Size: 180 x 75 nm

A

Vesicular Stomatitis Virus

56
Q

● Vector: Insect (Mosquito, Sand fly, Black fly)

A

Vesicular Stomatitis Virus

57
Q

● Host: Cattle, Horse, Pig, Deer, Human

A

Vesicular Stomatitis Virus

58
Q

● Bite by rabid dog or other animals

A

Rabies Virus

59
Q

● Virus ,multiply in the muscle connective tissue, nerves after 48-72 hours

A

Rabies Virus

60
Q

● If untreated % will developed rabies

A

50

61
Q

● Virus are carried in saliva virus deposited in the wound site

A

Rabies Virus

62
Q

● Animals: Insect bite

A

Vesicular Stomatitis Virus

63
Q

● Humans: Exposure to infected animal

A

Vesicular Stomatitis Virus

64
Q

● Direct immunofluorescence and Confirmation in the animal

A

Rabies Virus

65
Q

● PCR

A

JAPANESE AND ST. LOUIS ENCEPHALITIS VIRUS

Hep C Virus

Vesicular Stomatitis Virus

66
Q

● Rigorous cleansing of the bite wound, Vaccine for dogs and cat, HDCV for humans

A

Rabies Virus

67
Q

● Vector control, Good sanitation, PPE

A

Vesicular Stomatitis Virus

68
Q

● Headache, fever,sore throat,

A

Rabies Virus

69
Q

● Hallucinations

A

Rabies Virus

70
Q

● Pain or tingling at the site of the bite

A

Rabies Virus

71
Q

● Afraid of water - hydrophobia

A

Rabies Virus

72
Q

● Respiratory arrest, death in 1-6 days

A

Rabies Virus

73
Q

● Seizures

A

Rabies Virus

74
Q

● Difficulty in drinking

A

Rabies Virus

75
Q

Vesicular Stomatitis Virus

● Animals: on the feet, mouth, teats, and hooves

A

Blister-like lesions

76
Q

Vesicular Stomatitis Virus

● Humans: (?) symptoms

A

Influenza-like

77
Q

Detection of specific antibodies against rabies virus

A

Rabies Virus

78
Q

● Detection of antibodies against VSV

A

Vesicular Stomatitis Virus

79
Q

● 60-65 nm

A

Eastern,Western andEquineEncephalitis Virus

80
Q

● It has a single stranded, positive-sense RNA genome

A

Eastern,Western andEquineEncephalitis Virus

81
Q

● (German measles) is a generally mild, selflimited illness

A

Rubella Virus

82
Q

● A single member of the genus Rubivirus in the family Togaviridae.

A

Rubella Virus

83
Q

● Is a spherical, 40- to 80-nm, positive-sense, singlestranded RNA virus with spike-like

A

Rubella Virus

84
Q

● 60-70nm

A

Chikungunya

85
Q

● Spherical

A

Chikungunya

86
Q

● Positive-sense, single strand RNA genome surrounded by a lipid envelope

A

Chikungunya

87
Q

Virus enters the bloodstream via the saliva of an infected female mosquito

A

Eastern,Western andEquineEncephalitis Virus

88
Q

● Direct contact with the person who has rubella

A

Rubella Virus

89
Q

● Droplet contact with respiratory secretions

A

Rubella Virus

90
Q

● Possible transplacental infection of fetus during viremia

A

Rubella Virus

91
Q

virus infection begins when an infected mosquito bites a human and the virus is introduced into the skin and bloodstream.

A

Chikungunya

92
Q

The virus replicates in the fibroblasts of the dermis and disseminates through the bloodstream to several tissues.

A

Chikungunya

93
Q

Viral replication occurs in target tissues — mainly muscles, joints, and skin, as well as the liver, spleen, and meninges in neonates and patients with underlying conditions.

A

Chikungunya

94
Q

Inflammatory cells are recruited to infected tissues.

A

Chikungunya

95
Q

Joints (including in the fingers, wrists, elbows, knees, ankles, and toes) become inflamed in response to viral replication and inflammatory infiltrates.

A

Chikungunya

96
Q

● Serology and viral identification by PCR on a cerebrospinal fluid obtained after a lumbar puncture

A

Eastern,Western andEquineEncephalitis Virus

97
Q

● Blood tests

A

Rubella Virus

98
Q

● Nasal or throat swabs.

A

Rubella Virus

99
Q

● Urine tests

A

Rubella Virus

100
Q

● It may be detected directly in blood samples collected using test such as reverse transcriptase-polymerase chain reaction ( RT-PCR)

A

Chikungunya

101
Q

● There is no vaccine available

A

Eastern,Western andEquineEncephalitis Virus

102
Q

● Routine childhood immunization

A

Rubella Virus

103
Q

● Immunization of susceptible adolescent

A

Rubella Virus

104
Q

● Valneva vaccine

A

Chikungunya

105
Q

● Fever

A

Eastern,Western andEquineEncephalitis Virus

106
Q

● Severe depression ―sleeping sickness‖

A

Eastern,Western andEquineEncephalitis Virus

107
Q

● Behavior changes

A

Eastern,Western andEquineEncephalitis Virus

108
Q

● Impaired vision

A

Eastern,Western andEquineEncephalitis Virus

109
Q

● Circling or head pressing

A

Eastern,Western andEquineEncephalitis Virus

110
Q

● Muscle twitches

A

Eastern,Western andEquineEncephalitis Virus

111
Q

● Inability to swallow

A

Eastern,Western andEquineEncephalitis Virus

112
Q

● Paralysis

A

Eastern,Western andEquineEncephalitis Virus

113
Q

● Convulsions, Death

A

Eastern,Western andEquineEncephalitis Virus

114
Q

● Mild fever of 102 F (38.9 C) or lower

A

Rubella Virus

115
Q

● Headache

A

Rubella Virus

116
Q

● Stuffy or runny nose

A

Rubella Virus

117
Q

● Red, itchy eyes

A

Rubella Virus

118
Q

● Enlarged, tender lymph nodes

A

Rubella Virus

119
Q

● A fine, pink rash that begins on the face

A

Rubella Virus

120
Q

● Aching joints

A

Rubella Virus

121
Q

● High fever

A

Chikungunya

122
Q

● Rigors

A

Chikungunya

123
Q

● Headache

A

Chikungunya

124
Q

● Photophobia

A

Chikungunya

125
Q

● Petechial rash or maculopapular rash

A

Chikungunya

126
Q

● IgG Avidity Testing

A

Rubella Virus

127
Q

● Specific igM antibodies usually usually appear upon cessation of viremia, usually by day 5-7 into the illness and stay positive for 3 to 6 months

A

Chikungunya

MYCOLOGY AND VIROLOGY (24 decks)

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