1.6 Muscle Physiology Flashcards Preview

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Flashcards in 1.6 Muscle Physiology Deck (10):
1

determines the number of actin sites available for cross-bridge binding

Calcium

2

Extends along the length of the thin filament; aligns the actin

Nebulin

3

Largest known protein; participate in the formation of a scaffold for organization and lighnment of thick filaments

Titin

4

Stabilizes the sarcolemma and prevents contraction-induced injury (rupture)

Dystrophin-glycoprotein complex

5

Where calcium binds to cause the conformational change that exposes actin-myosin binding sites

Torponin C

6

Conformational change of this receptor after the propagation of action potential in the T tubule opens calcium release channels in the SR

Dihydropyridine receptor (DHP)

7

Slips into the groove of the actin filament and exposes myosin-binding sites on the actin filament after binding of calcium to troponin C

Tropomyosin

8

Helps accumulate Ca2+ in the terminal cisternae

Calsequestrin

9

This action allows the myosin to detach from actin

Binding of ATP to myosin

10

Resting membrane potential of muscle is

-90 mV