Samplex 1st LE Flashcards Preview

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Flashcards in Samplex 1st LE Deck (34):
1

This protein attaches to membrane proteins destined for endocytosis and eventual degradation in the lysosomes

Ubiquitin

2

Proteins destined to be secreted or targeted out of the plasma membrane are processed in the...

Rough ER

3

Type of diffusion where carrier undergoes conformational change:

Facilitated diffusion

4

Co transport molecule of glucose

Sodium

5

Used for cholesterol uptake

Receptor- mediated endocytosis

6

A form of bull transport by which a hormone is secreted when the appropriate signal is received by the cell is:

Regulated exocytosis

7

Phosphorylation of g protein coupled receptor results in

Inactivation of receptor

8

Activation of this effector g protein results in the activation of creb protein

Adenylyl cyclase

9

Activation of plc results in an increase of cytosolic calcium because of the opening of

Ip3 gated calcium channels in the erStore operated calcium channels

10

Binding of a ligand to a tyrosine kinase receptor causes

Autophosphorylation of the receptor

11

Cytokine receptors acitvate loosely associated tyrosine kinases known as

JAK

12

Transcription factor activated by receptor serine-threonjbe kinase

SMAD

13

Phosphorylated insulin receptor can activate this

MAPK

14

Receptor for ligand epinephrine

G protein coupled receptor

15

Receptor for estrogen

Intracellular

16

Receptor for TGF-B

Serine threonine kinase receptor

17

Neuron that sends impukses towards the cns

Afferent unipolar

18

In rmp, ions move through which channel

Leak channels

19

Local potential exhibited by a sensory neuron

Generator potential

20

Equation on concentration of ions in rmp

GoldmanHodgkinKatz

21

The spike potential determines this neuron property

Excitability

22

The duration of action potential is the

Spike potential

23

The critical firing level

Threshold potential

24

Hyperpolarization occurs during what period

Relative refractory period

25

Toxin that blocks voltage gated sodium channels; from puffer fish

Tetrodotoxin

26

Toxin blocks nmj ach receptor; from snake venom

Bungarotoxin

27

Blocks voltage gated potassium channels

Apamin from honeybee

28

Viltage gated sodium channel is most dense at the

Nodes of ranvier

29

Susceptibility trend to hypoxia

B>A>C

30

Neuron fiber susceptibility to pressure

ABC

31

Neuron fiber susceptibility to local anesthetics

CBA

32

Increases the likelihood of an action potential on the PSN

Temporal and spatial summation

33

Is the simultaneous firing of neurons

Spatial summation

34

Increasing the frequency if stimulation of the neurons

Temporal summation