Flashcards in 17. Hematology Deck (21):
What's the most common factor deficiency?
What do you use to follow warfarin?
What is PTT in warfarin?
Prolonged - because common pathway is also affected (PT just does a better job of following warfarin)
What is PT in heparin?
Prolonged - because common pathway is also affected (PTT just does a better job of following heparin)
What's the best test for DIC?
D-dimers (fibrin split products - fibrin that is crosslinked)
Small red dots everywhere - telangiectasias?
Hereditary telangiectasias - iron deficiency anemia from GI bleeds
HSR of ITP?
What happens in ITP?
IgG against platelets
TTP/HUS vs. DIC?
TTP/HUS has normal coagulation factors; not using those up
What do we see on blood smear for TTP?
Hem A vs. vWD?
vWD has factor 8 deficiency in addition to platelet problems - menorrhagia in addition to petechiae, etc.
What is drug of choice for vWD?
Why does amniotic fluid in the circulation cause problems?
Thromboplastin --> DIC
What is the most common hereditary thrombosis?
Factor V Leiden
Hx of thrombosis, patient started on heparin, PTT is normal - diagnosis?
Antithrombin III deficiency
What is the most common way antithrombin III deficiency is acquired?
anti-A and anti-B blood group antibodies are what kind of immunoglobulin?
What groups of patients have low/no blood group immunoglobulins?
Babies and elderly
What blood group is associated with gastric cancer?
What blood group is associated with ulcers?