17. Hematology Flashcards Preview

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Flashcards in 17. Hematology Deck (21):
1

What's the most common factor deficiency?

Factor VIII

2

What do you use to follow warfarin?

PT

3

What is PTT in warfarin?

Prolonged - because common pathway is also affected (PT just does a better job of following warfarin)

4

What is PT in heparin?

Prolonged - because common pathway is also affected (PTT just does a better job of following heparin)

5

What's the best test for DIC?

D-dimers (fibrin split products - fibrin that is crosslinked)

6

Small red dots everywhere - telangiectasias?

Hereditary telangiectasias - iron deficiency anemia from GI bleeds

7

HSR of ITP?

II

8

What happens in ITP?

IgG against platelets

9

TTP/HUS vs. DIC?

TTP/HUS has normal coagulation factors; not using those up

10

What do we see on blood smear for TTP?

schistocytes

11

Hem A vs. vWD?

vWD has factor 8 deficiency in addition to platelet problems - menorrhagia in addition to petechiae, etc.

12

What is drug of choice for vWD?

Desmopressin (DDAVP)

13

Why does amniotic fluid in the circulation cause problems?

Thromboplastin --> DIC

14

What is the most common hereditary thrombosis?

Factor V Leiden

15

Hx of thrombosis, patient started on heparin, PTT is normal - diagnosis?

Antithrombin III deficiency

16

What is the most common way antithrombin III deficiency is acquired?

OCP's

17

anti-A and anti-B blood group antibodies are what kind of immunoglobulin?

IgM

18

What groups of patients have low/no blood group immunoglobulins?

Babies and elderly

19

What blood group is associated with gastric cancer?

A

20

What blood group is associated with ulcers?

O

21

Why are blacks less likely to get plasmodium vivax?

Black populations lack duffy antigen on erythrocytes which vivax needs to infect