19_Cell-cell interactions Flashcards Preview

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Flashcards in 19_Cell-cell interactions Deck (12)
1

Which cell-cell interactions are calcium-dependent?

cadherin-cadherin and selectin-lectin interactions

2

Which type of intercellular interactions help establish spatial order in embryogenesis?

cadherin-cadherin interactions

3

How is spatial order established in embrogenesis?

Cells from different germ layers have distinct adhesive properties. These selective cell affinities help establish spacial order of different tissues within the embryo through cadherin-cadherin interactions.

4

What do IgSF proteins interact with in cell-cell adhesion?

other IGSF members OR integrins

5

Which class of adhesion proteins do ICAMs belong to?

IgSF

6

What is an example of an IgSF important to neural development?

L1

7

What are ICAMs in blood vessels called?

VCAMs

8

What are the domains of IgSF proteins?

Fn (Fibronectin) III & Ig

9

What class of proteins act as receptors for ICAMs?

Integrins

10

What types of selectins are present on endothelial cells?

E- and P-selection

11

What cell-cell interaction protein is initially upregulated in endothelial cells in response to inflammation?

selectin

12

What is the function of IL-8 in neutrophil trapping?

activates G-protein coupled receptors on neutrophil => activates integrins on neutrophil