12_Location, Location, Location Flashcards Preview

BIOL 331 > 12_Location, Location, Location > Flashcards

Flashcards in 12_Location, Location, Location Deck (16)
1

Where is ceramide converted into complex sphingolipids?

Golgi

2

On which end of the protein MUST the signal sequence lie for proteins imported into mitochondria and chloroplasts?

amino

3

What is the signal sequence for import into peroxisomes? Which end of the protein is it on?

SKL-COOH

4

Do peroxisomes have their own DNA?

no

5

What are peroxisomes?

Membrane-bound organelles containing oxidative enzymes

6

What do the enzymes in peroxisomes oxidize? What is formed?

Oxidize long-chain fatty acids to synthesize plasmalogens

7

What toxic compound is formed as a by-product in peroxisomes? How is it broken down?

H2O2; broken down by catalase

8

What signal mediates uptake of proteins into peroxisomes?

PTS (peroxisomal targeting signal)

9

What sequence on proteins can target them for uptake into mitochondria? Chloroplasts?

M: presequence
C: transit peptide

10

For proteins to be uptaken into mitochondria, they must be (folded/unfolded).

unfolded

11

What type of protein is Hsp70?

chaperone

12

What does a protein interact with in the outer mitochondrial membrane?

TOM complex

13

What cleaves the presequence once a protein is uptaken into a mitochondrion?

MPP (mitochondrial processing peptidase)

14

Which phopholipids are abundant in the IMM?

CL and PG

15

Which TIM complex do proteins that will be embedded into the IMM interact with?

TIM 22

16

Proteins are imported (folded/unfolded) into peroxisomes.

folded