Flashcards in 28_Cell Cycle I Deck (9)
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1
What does flow cytometry quantify?
Number cells as a function of DNA content per cell
2
What phase of the cell cycle are the majority of cells in a culture in at a given time?
Which phase contains the least number of cells?
most: G1
least: S
3
What is the result of fusing M-phase and S-phase cells?
chromosomal damage (pulverized DNA) due to compaction of actively dividing DNA.
4
MPFs have 2 subunits; what are they?
CDK & a cyclin
5
What is the effect of increasing cyclin concentration on CDKs?
they are activated => initiate entry into mitosis
6
Which is degraded more, CKDs or cyclins?
cyclins
7
What is the CDK in yeast?
cdc2 kinase -- only has this one
8
When is MPF activity the highest?
M-phase
9
