Flashcards in 21_Cell Junctions II Deck (8)
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1
Which cell-cell junctions form the paracellular pathway?
tight junctions
2
Disorders involving thin hair, retinal degradation and limb malformation are a result of mutations in which cell adhesion protein?
cadherin
3
What are symptoms of plakophilin mutations?
kinky hair and fragile skin
4
Where is keratin 14 expressed? What are the consequences of weak keratin 14?
basal cell layer of epidermis
blister in same layer; fragile skin
5
What type of cells make up most of the lens?
Fibre cells
6
How do gap junction connexins maintain lens transparency?
GJs to other cells maintain ion flow and promote crystallin cytoplasmic protein function & structure
7
What is a ocular consequence of gap junction mutations?
cloudy lens
8
