Flashcards in 21_Cell Junctions II Deck (8)
Which cell-cell junctions form the paracellular pathway?
Disorders involving thin hair, retinal degradation and limb malformation are a result of mutations in which cell adhesion protein?
What are symptoms of plakophilin mutations?
kinky hair and fragile skin
Where is keratin 14 expressed? What are the consequences of weak keratin 14?
basal cell layer of epidermis
blister in same layer; fragile skin
What type of cells make up most of the lens?
How do gap junction connexins maintain lens transparency?
GJs to other cells maintain ion flow and promote crystallin cytoplasmic protein function & structure
What is a ocular consequence of gap junction mutations?