2-drug names Flashcards

1
Q

fluoxetine

A

prozac, SSRI

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2
Q

venlafaxine

A

effexor, SNRI

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3
Q

norfluoxetine

A

metabolized product of fluoxetine

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4
Q

desvenlafaxine

A

metabolized product of venlafaxine

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5
Q

vigabtrin

A

irreversible inhibitor of GABA-transaminase

for partial seizures

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6
Q

tiagabine

A
inhibits GAT (GABA transporter that removed GABA from synaptic cleft)
good for partial seizures, "add-on" therapy
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7
Q

carbazepine

A

use-dependent block of APVG Na channel, locks channels into inactivates state
prevents abnormal discharge rates

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8
Q

parampanel

A

AMPA receptor allosteric inhibitor (Decreases excitatory influence)
good for seizures but not absense

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9
Q

pentobarbital

A

barbiturate

allosteric modulator that increases length of time that GABA channel opens

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10
Q

triazolam

A

benzodiazepine
allosteric modulator that increases frequency that GABA channel opens

sleep aid, 2h half life, causes memory impairment and violence

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11
Q

diazepine

A

benzodiazepine

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12
Q

zaleplon, zolpidem, zopiclone

A

z drugs, short half life, still bind to GABA-A (sleep)

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13
Q

suvorexant

A

orexin receptor antagonist (sleep)

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14
Q

haloperidol

A

1st gen typical antipsychotic

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15
Q

chlorpromazine

A

1st gen typical antipsychotic

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16
Q

clozapine

A

2nd gen atypical antipsychotic

17
Q

risperidone

A

2nd gen atypical antipsychotic

18
Q

nabilone

A

synthetic analog of THC, taken orally

19
Q

dronabinol

A

isomer of THC

good for nausea and appetite, taken orally

20
Q

nabiximols

A

1:1 THC and cannabinol (non psychoactive)

pain for MS and cancer

21
Q

rimonabant

A

inverse agonist at CB1

good for obesity but bad for depression and suicide

22
Q

AEA and 2-AG

A

endocannabinoids

retrograde neurotransmitters

23
Q

buprenorphine

A

partial agonist mu, antagonist delta kappa

treatment for pain and opioid addiction

24
Q

endorphins

A

mu

25
Q

enkephalins

A

delta

26
Q

dynorphins

A

kappa

27
Q

Ethosuximide

A

Blocks t type calcium to prevent abnormal firing rates

Absence seizures