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Flashcards in 2. Transmission of Infection Deck (18)
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1

Basic chain of infection (6)

Infectious agent
Reservoir
Portal of exit
Means of transmission
Portal of entry
Susceptible host

2

Definition of virulence

Ability of the microbe to cause disease

3

Definition of dose

Number of microbes entering the body

4

Types of virulence factors (2)

Exotoxins
Endotoxins

5

Definition of infectious dose

Dose required to cause infections (ID50)

6

Definition of incubation period

Time between contamination and development of symptoms
Varies widely for different infections

7

Longer incubation periods permit (2)

Longer time period when infecting microbe may be spread to others
Greater spread of disease due to more human contact

8

Definition of asymptomatic carrier

Infected person with no clinical evidence of disease (although signs and symptoms may have been evidence earlier)

9

Definition of colonisation

Presence of micro-organisms in/on a host, with growth and multiplication, but without any overt clinical expression at the time of isolation

10

Modes of microbe escape (2)

Natural (cough, sneeze)
Artificial (blood donation)

11

Composition of influenza

RNA virus with segmented genome

12

Types of influenza (3)

Type A
Type B
Type C

13

Surface glycoproteins found on influenza type A and B (2)

Haemagglutinin H1-15
Neuraminidase N1-9

14

What do influenza type A and B cause

Major outbreaks

15

Incubation period for influenza

2-3 days

16

Rhinovirus portals of entry (4)

Respiration (aerosols)
Inhalation (all particles)
Direct contact (droplets)
Indirect contact (settled particles)

17

Rhinovirus susceptible hosts (6)

Those with complicated infections
Unvaccinated
Elderly
Young children
Pregnant women
Chronic medical condition sufferers (diabetes, asthma, heart disease)

18

Function of the influenza virus (2)

Break chain of infection
Prevent transmission of influenza virus