Histology - Male Reproductive System Flashcards

1
Q

seminiferous, open, euchromatic -nucleolus

A

Sustentacular cell

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1
Q

“checkerboard” nucleus, middle layer

A

Primary spermatocyte

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2
Q

low back pain, urethral discharge, fever. Expressed prostatic secretions (EPS) culture

A

Prostatitis

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3
Q

Testis Septa

A

CT that divides testis into lobules

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3
Q

the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.

A

Seminiferous tubules

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3
Q

tumors that arise from sustentacular cells or interstitial cells

A

Sex cord-stromal tumors

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4
Q

Testis dense CT capsule

A

Tunica albuginea

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6
Q

inflammatory response within IT of testis (e.g., viral mumps in adults, syphilis)

A

Orchitis - scarring may cause infertility, T production often not significantly affected

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7
Q

produce sperm

A

spermatogenic cells

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8
Q

Semiferous epithelium, 3 layers

A

Seminiferous (germinal) epithelium, basement membrane, tunica propria

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9
Q

nuclei along the BM

A

Spermatogonia

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9
Q

Found from transitional zone. Associated with DHT, stromal cells convert T to DHT, dysuria, secondary UTIs (urine retention)

A

Benign prostatic hyperplasia (BPH)

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10
Q

have the appearance of a mucus-secreting gland. lubricates the urethra with pre-seminal mucus

A

bulbourethral glands

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12
Q

produce testosterone (T)

A

interstitial cells (of Leydig)

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13
Q

defining histologyical feature of prostate gland

A

prostatic concretions

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14
Q

testis are responsible for…

A

spermatogenesis: exocrine (holocrine) secretion of sperm AND steroidogenesis: endocrine secretion of testosterone

15
Q

yield primary spermatocytes by mitosis…

A

spermatogonia

16
Q

disruption of the B-T barrier, antisperm antibodies (ASA)

A

Immune infertility

17
Q

The seminiferous tubules are formed from…

A

primitive sex cords. It is the medullary cords which develop into the seminiferous tubules and the cortical cords regress. The cords were formed from the gonadal ridge.

18
Q

Interstitial tissue (IT) loose connective tissue stroma that contains…

A

fenestrated capillaries, interstitial cells (of Leydig): produce testosterone (T)

20
Q

Tumors that arise from spermatogenic cells;

A

Germ cell tumors, most common (95%).

21
Q

regulates glandular epithelium growth and metabolism

A

Prostatic acid phosphatase (PAP)

22
Q

small, dark nucleus, near lumen

A

Spermatid

23
Q

produce ABP, MIS, inhibin, fructose-rich fluid

A

sustentacular (Sertoli) cells

24
Q

days until the effects of an antispermatogenic agent are fully observable

A

86 days, 74 in testis, 12+ to mature in epididymis

25
Q

Formed by tight junctions between sustentacular cells

A

Blood-testis barrier. Sequesters testosterone in luminal compartment -necessary for spermatogenesis. Gap junctions coordinate activity.

26
Q

Seminiferous tubules epithelium

A

sustentacular or Sertoli cells, which are tall, columnar type cells that line the tubule.

27
Q

primary spermatocyte divides meiotically into …

A

two secondary spermatocytes. Each secondary spermatocyte then completes meiosis as it divides into two spermatids which developninto mature spermatozoa (sperm cells).

29
Q

Seminiferous (germinal) epithelium:

A

spermatogenic cells and sustentacular cells

30
Q

most resistant to BPH, prostatitis, & cancer

A

Central zone