Chapter 14 - Part 1

Question 1

what percent of the population is affected by Aphthous Ulcers? (Canker Sores)

Answer 1

40%

Question 2

what condition is defined as a shallow ulceration on the oral mucosa

Answer 2

Aphthous Ulcer (Canker Sore)

Question 3

Canker Sores are painless ulcerations that are >5mm

Answer 3

False, they are painful and <5mm

Question 4

Aphthous Ulcers (Canker Sores) are noncontagious and thought to have an autoimmune component

Answer 4

true

Question 5

what is the severe version of Aphthous Ulcers in which there is severe ulceration in the mouth including the back of the throat and possibly even genitally called?

Answer 5

Behcet Disease

Question 6

Cold Sores are another name for what?

Answer 6

Herpes Simplex Virus

Also: Herpetic Stomatitis or fever blisters

Question 7

20% of people with Herpes Simplex Virus are Asymptomatic and the other 80% have acute gingivostomatitis

Answer 7

False

80% are Asymptomatic and the remainder have the acute gingivostomatitis

Question 8

Where does the initial infection of Herpes Simplex Virus remain latent?

Answer 8

Trigeminal Ganglion (CN V)

Question 9

What is the location of HSV-1 and HSV-2?

Answer 9

HSV-1 - Orofacial

HSV-2 - Genital

Question 10

A patient comes to you complaining of a small cluster of blister like lesions on the corner of their mouth. They report some burning and tingling around the area. and mention they had a similar thing happen about a month ago. Upon inspection what do you think this may be?

Answer 10

the recurring blisterlooking lesions are vesicles that appear with Herpes Simplex Virus

Question 11

Is there a cure for Herpes Simplex Virus?

Answer 11

No

Question 12

Why is Herpes Simplex Virus a serious condition?

Answer 12

this is a viral infection which can spread to the brain and possibly cause herpesviral encephalitis

Question 13

If the Herpes simplex virus spreads to the brain which type is it typically? HSV-1 or HSV-2?

Answer 13

HSV-1

Question 14

What is the most common oral fungal infection?

Answer 14

Oral Candidiasis

Question 15

Is Oral Candidiasis an opportunistic infection

Answer 15

Yes

Question 16

A mom brings in their baby and is concerned about a while “membrane” on the baby’s tongue. She had previously thought it looked like milk and went to scrape it off but noticed it was very red underneath and this upset the baby. What is your diagnosis

Answer 16

Oral Candidiasis,

- Pseudomembranous Candidiasis (thrush)

Question 17

What is the condition in which there is an overgrowth of capillaries in the gingiva that is sometimes referred to as a “pregnancy tumor”

Answer 17

Pyogenic Granuloma

Oral Proliferative Lesion

Question 18

what is a firm, raised, white patch/lesion that cannot be scraped off (is firmly adhered) in the mouth called?

Answer 18

leukoplakia

Question 19

Leukoplakia is relatively rare, only 3% of the population gets this, but of those who do have it what percent are pre cancerous?

Answer 19

25%

Question 20

What population is Leukoplakia usually seen in?

Answer 20

more common in males between 40 and 70

Question 21

what is the term for a pre cancerous, raised white lesion in the mouth?

Answer 21

Leukoplakia

Question 22

What is a red velvety area in the mouth that has irregular borders

Answer 22

Erythroplakia

Question 23

Erythroplakia is associated with tobacco used

Answer 23

True

Question 24

are men or women more likely to have oral cancer?

Answer 24

men

Question 25

which is more likely to transition into oral cancer? Leukoplakia or Erythroplakia?

Answer 25

Erythroplakia | - 50% of the time

Question 26

What is the mutation associated with oral cancer

Answer 26

TP53 Mutation "guardian of the genome"

Question 27

95% of Oral cancers are associated with which cells?

Answer 27

Squamous cell carcinomas

Question 28

mouth/throat pain that may cause difficulty swallowing or speaking along with multiple primary tumors is a sign of what?

Answer 28

Oral Cancer

Question 29

Oral cancer is most likely to have a single primary tumor develop in the mouth

Answer 29

False, MULTIPLE primary tumors are most common

Question 30

usually over 50% of people with oral cancer survive long term

Answer 30

False, poor prognosis - LESS THAN 50% long term survival once diagnosed

Question 31

T or F oral cancer that is positive for HPV 16 has a more favorable prognosis than those without this association?

Answer 31

True | - this is associated with fewer mutations

Question 32

A patient comes in complaining of mouth pain and upon inspection you discover they have a raised, firm lesion with irregular borders under their tongue. What do you suspect

Answer 32

Squamous Cell Carcinoma

Question 33

What is the most common location oral cancer is going to go?

Answer 33

Cervical Nodes

Question 34

Squamous Cell Carcinoma most likely metastasizes via lymph system or by hematogenous system?

Answer 34

By lymph system | (Carcinoma)