what percent of the population is affected by Aphthous Ulcers? (Canker Sores)
what condition is defined as a shallow ulceration on the oral mucosa
Aphthous Ulcer (Canker Sore)
Canker Sores are painless ulcerations that are >5mm
False, they are painful and <5mm
Aphthous Ulcers (Canker Sores) are noncontagious and thought to have an autoimmune component
what is the severe version of Aphthous Ulcers in which there is severe ulceration in the mouth including the back of the throat and possibly even genitally called?
Cold Sores are another name for what?
Herpes Simplex Virus
Also: Herpetic Stomatitis or fever blisters
20% of people with Herpes Simplex Virus are Asymptomatic and the other 80% have acute gingivostomatitis
80% are Asymptomatic and the remainder have the acute gingivostomatitis
Where does the initial infection of Herpes Simplex Virus remain latent?
Trigeminal Ganglion (CN V)
What is the location of HSV-1 and HSV-2?
HSV-1 - Orofacial
HSV-2 - Genital
A patient comes to you complaining of a small cluster of blister like lesions on the corner of their mouth. They report some burning and tingling around the area. and mention they had a similar thing happen about a month ago. Upon inspection what do you think this may be?
the recurring blisterlooking lesions are vesicles that appear with Herpes Simplex Virus
Is there a cure for Herpes Simplex Virus?
Why is Herpes Simplex Virus a serious condition?
this is a viral infection which can spread to the brain and possibly cause herpesviral encephalitis
If the Herpes simplex virus spreads to the brain which type is it typically? HSV-1 or HSV-2?
What is the most common oral fungal infection?
Is Oral Candidiasis an opportunistic infection
A mom brings in their baby and is concerned about a while “membrane” on the baby’s tongue. She had previously thought it looked like milk and went to scrape it off but noticed it was very red underneath and this upset the baby. What is your diagnosis
- Pseudomembranous Candidiasis (thrush)
What is the condition in which there is an overgrowth of capillaries in the gingiva that is sometimes referred to as a “pregnancy tumor”
Oral Proliferative Lesion
what is a firm, raised, white patch/lesion that cannot be scraped off (is firmly adhered) in the mouth called?
Leukoplakia is relatively rare, only 3% of the population gets this, but of those who do have it what percent are pre cancerous?
What population is Leukoplakia usually seen in?
more common in males between 40 and 70
what is the term for a pre cancerous, raised white lesion in the mouth?
What is a red velvety area in the mouth that has irregular borders
Erythroplakia is associated with tobacco used
are men or women more likely to have oral cancer?
which is more likely to transition into oral cancer? Leukoplakia or Erythroplakia?
- 50% of the time
What is the mutation associated with oral cancer
TP53 Mutation “guardian of the genome”
95% of Oral cancers are associated with which cells?
Squamous cell carcinomas
mouth/throat pain that may cause difficulty swallowing or speaking along with multiple primary tumors is a sign of what?
Oral cancer is most likely to have a single primary tumor develop in the mouth
False, MULTIPLE primary tumors are most common
usually over 50% of people with oral cancer survive long term
False, poor prognosis - LESS THAN 50% long term survival once diagnosed
T or F oral cancer that is positive for HPV 16 has a more favorable prognosis than those without this association?
- this is associated with fewer mutations
A patient comes in complaining of mouth pain and upon inspection you discover they have a raised, firm lesion with irregular borders under their tongue. What do you suspect
Squamous Cell Carcinoma
What is the most common location oral cancer is going to go?
Squamous Cell Carcinoma most likely metastasizes via lymph system or by hematogenous system?
By lymph system