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Reproduction and Sexuality > 3.4.3 Uterine Pathology > Flashcards

3.4.3 Uterine Pathology Flashcards

(45 cards)

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1
Q

What is this an image of?

A

Endometrial adenocarcinoma with squamous differentiation

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2
Q

What are the clinical features and treatment of endometrial carcinoma?

A
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3
Q

What is this an image of and what are the characteristics?

A
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4
Q

What are the characteristics of the Secretory phase?

A

Last 14 days

Progesterone

Secretions

Coiled glands

Edematous stroma

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5
Q

What is endometrial hyperplasia?

A

Increase in the number of glands relative to the stroma (crowded glands)

Clinical importance - common cause of abnormal bleeding and precursor lesion of the most common form of endometrial carcinoma

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6
Q

What are the covered parts?

A
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7
Q

What is this an image of?

A

Villo-glandular adenocarcinoma

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8
Q

What are is the pathogenesis and clinical features of endometriosis?

A
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9
Q

What is a leiomyoma?

A

Benign Smooth muscle tumor

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10
Q

What is the treatment of endometrial hyperplasia?

A

Hormonal - high dose progestins

Hysterectomy

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11
Q

Describe the progression of proliferative endometrium to Grade 1 uterine endometroid carcinoma.

A
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12
Q

How will the stroma appear in the secretory phase?

A

Stromal edema

Prominent arterioles

Predecidualization

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13
Q

What is adenomyosis?

A

Endometrial glands an stroma in the myometrium

Pathology - glands and stroma, Gross - red soft areas in the myometrium

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14
Q

What is this an image of?

A

Malignant Mixed Mullerian Tumor

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15
Q

What are the characteristics of leiomyosarcoma?

A
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16
Q

What are these images of?

A

Endometrial polyp w Complex hyperplasia

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17
Q

What is the difference between these?

A
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18
Q

What are these images of?

A

Leiomyosarcoma

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19
Q

What are these images of?

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A

Low grade endometrial sarcoma

Left - desmin stain

Right - CD10 stain

20
Q

What are the common risk factors associated with endometrial andenocarcinoma?

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A

Prolonged estrogen exposure

21
Q

What phase is this in? What is important to note?

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A

This is in the secretory phase

There is stroma edema

22
Q

What are the basic characteristics of acute and chronic endometritis?

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A

Acute - PMNs: Ascending infection, abortion, or instrumentation

Chronic - Plasma cells - IUD, PID, abortion

Clinically - bleeding and pelvic pain - self limiting

23
Q

What is this an image of?

Study These Flashcards
A

MMMT

Left arrow - cartilage

Right - rhabdomyosarcoma

24
Q

What are the clinical features and treatment of Leiomyoma?

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A

Clinical features - Depends on location, symptomatic, DUB, Mass, others

Treatment - Myometcomy, Hysterectomy, Laparoscopic uterine artery embolization or ligation in women who want to preserve fertility

25
What are the covered parts and what are these?
26
What are the pathological findings associated with endometriosis?
Red Blue areas **(Mulberry Nodules)** Powder burns secondary to hemosiderin Fibrous adhesions Endometrial glands and stroma Hemorrhage and fibrosis
27
What are the histological characteristics of Endometrial polyps?
Endometrial glands, cysts and hyperplasia Fibrous stroma Thick-walled blood vessels
28
How will glands appear in the secretory phase?
Subnuclear vacuoles Supranuclear vacuoles Intraluminal secretions
29
How do you classify endometrial hyperplasia?
30
What are these images of?
Low grade endometrial sarcoma
31
What are the clinical features of endometrial hyperplasia?
Tumor, obesity, PCO, estrogen therapy Uterine bleeding
32
What are the gross and histological characteristics of endometrial adenocarcinoma?
33
What are the characteristics of the proliferative phase?
First 14 days Estrogen Proliferation Tubular Glands Monomorphic Stroma
34
What is this an image of?
adenomyosis
35
What is this an image of?
Secretory adenocarcinoma
36
What is the WHO classification of Endometrial hyperplasia?
37
What are the covered parts?
38
What are the HONDA risk factors?
H - Hormones O - Obesity N - Nulliparous D - Diabetes A - Aging
39
What is this an image of?
Benign endometrial hyperplasia Cystic hyperplasia
40
What are the important findings in each of these images?
Left 2 - Sub and supra nuclear vacuoles RIght - intraluminal secretions
41
What are the difference between the type I and type II endometrial carcinoma?
42
What is endometriosis?
Endometrial glands and stroma outside of the uterus Can be in the ovaries, tubes or round ligaments
43
How does the image on the left compare to the image on the right?
Left - proliferative Right - secretory
44
What is this an image of?
Leiomyosarcoma
45
What are the covered parts?
Left - acute infection - PMNs Rigt - chronic infection - plasma cells

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