Lipids V

Question 1

What does transport of lipids require

Answer 1

assembly of lipoprotein complex with hydrophilic surface and lipophilic core

Question 2

function of HSL

Answer 2

release FFA into circulation from storage triglycerides

Question 3

what hormones does HSL response to

Answer 3

insuline
cortisol
glucagon

Question 4

how does insulin affect HSL

Answer 4

inhibit

Question 5

how does cortisol affect HSL

Answer 5

induces

Question 6

how does glucagon affect HSL

Answer 6

stimulate

Question 7

function of apoproteins of A class

Answer 7

activators of LCAT

Question 8

function of apoproteins of B class

Answer 8

strucutral proetins that give lipoporetin its shap

Question 9

function of apoportins of C class

Answer 9

modulat function of LPL.

Question 10

function of apoporteins of E class

Answer 10

removal of lipid-depleted lipoproteins from circulation

Question 11

functino of enterocytes

Answer 11

resynthesize tricyglycerols and pack them into chylomicrons for distribution throughout the body

Question 12

where do newly synthesized chylomicrons go

Answer 12

secreted into lymphatic system and enter blood through thoracic duct

Question 13

function of chylomicrons

Answer 13

distribution of dietary lipids trhough the body

Question 14

functino of lipoprotein lipases on surface of target cells

Answer 14

cleave triacyclglycerols and liberate FFA from chylomicrons

Question 15

what removed chylomicron remnants from circulation

Answer 15

liver

Question 16

what binds to LDL recpetos on surface of liver cell

Answer 16

apoporteins ApoB48 and ApoE

Question 17

VLDLs

Answer 17

synthesized by liver to distribute lipids into peripheral tissue

Question 18

what happens when VLDLs lose lipds

Answer 18

turn into IDLs

Question 19

what happens when IDLs lose lipids

Answer 19

turn into LDLs

Question 20

when does blood conc of LDL increase

Answer 20

if liver sends out more lipids in VLDL particules than the body can consum

Question 21

what Apoportin does VLDLs synthesize around

Answer 21

ApoB100

Question 22

what are VLDLs capable of

Answer 22

extracting cholesteryl esters from cells

Question 23

HDL function

Answer 23

reverse cholesterol transport from peripheral tissues to liver

Question 24

how do HDL particules acquire choelsteral from periphal tissues

Answer 24

1. choelsteral transport by ABCA-1

2. choelteral transferred to HDL particle adn esterfiled by LCAT.