48. Inflammations and fibrocystic changes of the breast, fibroepithelial tumors Flashcards

1
Q

48-1. inflammation of breast

types of breast inflammation (4)

A

acute mastitis
periductal mastitis
mammary duct ectasia
fat necrosis

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2
Q

48-1. inflammation of breast

etiology of acute mastitis

A

bacterial infection (staphylococcus aureus), usually due to breast feeding

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3
Q

48-1. inflammation of breast

clinical symptoms of acute mastitis (3)

A

erythematous breast
purulent discharge
abscess

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4
Q

48-1. inflammation of breast

etiology of periductal mastitis

A

common in smoker

vitamin A deficiency, cause squamous metaplasia -> blocking

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5
Q

48-1. inflammation of breast

manifestation of periductal mastitis (2)

A

subareolar mass

nipple retraction

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6
Q

48-1. inflammation of breast

manifestation of mammary duct ectasia (3)

A

periareolar mass
retraction of nipple
green brown discharge

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7
Q

48-1. inflammation of breast

etiology of fat necrosis

A

trauma

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8
Q

48-1. inflammation of breast

manifestation of fat necrosis (2)

A

mass on physical exam

calcification on mammography

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9
Q

48-2. fibrocystic change of the breast

epidemiology, site of fibrocystic change

A

30-50 years old women

usually in upper outer quadrant

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10
Q

48-2. fibrocystic change of the breast

types of fibrocystic changes of breast

A
non proliferative
- cystic metaplasia
- fibrosis metaplasia
proliferative
- ductal hyperplasia
- sclerosing adenosis
- atypical hyperplasia
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11
Q

48-2. fibrocystic change of the breast

risk of malignancy

A

no risk : cyst metaplasia, fibrosis metaplasia
x2 risk : ductal hyperplasia, sclerosing adenosis
x5 risk : atypical hyperplasia

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12
Q

48-3. fibroepithelial tumor

subtypes of fibroepithelial tumor (3)

A

intraductal papilloma
fibroadenoma
phyllodes tumor

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13
Q

48-3. fibroepithelial tumor

morphology of intraductal papilloma

A

fibrovascular projection into the duct

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14
Q

48-3. fibroepithelial tumor

clinical manifestation of intraductal papilloma

A

bloody discharge

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15
Q

48-3. fibroepithelial tumor

differentiation between intraductal papilloma vs. papillary carcinoma

A

intraductal papilloma : epithelial cell + myoepithelial cell (2 lines)
papillary carcinoma : epithelial cell without myoepithelial cell (1 line)

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16
Q

48-3. fibroepithelial tumor

clinical manifestation of fibroadenoma

A

well circumscribed, mobile mass

17
Q

48-3. fibroepithelial tumor

characteristics of fibroadenoma

A

most common benign tumor of breast
no risk of malignancy
estrogen sensitive

18
Q

48-3. fibroepithelial tumor

morphology of phyllodes tumor

A

fibroadenoma like tumors with overgrowth of fibrous component
: leaf like projection

19
Q

48-3. fibroepithelial tumor

characteristics of phyllodes tumor

A

common in postmenopausal women

risk of malignancy