55. Pathology of the hypothalamic-hypophysis system Flashcards

1
Q
  1. Pathology of the hypothalamic-hypophysis system

etiology of hyperpituitarism (2)

A

pituitary adenoma

extrapituitary tumor

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2
Q
  1. Pathology of the hypothalamic-hypophysis system

subtypes of pituitary adenoma

A
functional
- prolactinoma
- somatotroph adenoma
- corticotroph adenoa
- gonadotroph adenoma
- thyrotroph adenoma
non functional
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3
Q
  1. Pathology of the hypothalamic-hypophysis system

clinical manifestation of prolactinoma (4)

A

galactorrhea
amenorrhea
loss of libido
headache

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4
Q
  1. Pathology of the hypothalamic-hypophysis system

clinical manifestation of somatotroph adenoma (2)

A

gigantism (child)

acromegaly (adult)

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5
Q
  1. Pathology of the hypothalamic-hypophysis system

clinical manifestation of corticotroph adenoma

A

cushing syndrome

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6
Q
  1. Pathology of the hypothalamic-hypophysis system

etiology of hypopituitarism (2)

A

physical damage : cause empty sella syndrome (enlargemet of bone around pituitary)
sheehan syndrome : pregnancy related infarction

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7
Q
  1. Pathology of the hypothalamic-hypophysis system

hyperfunction of posterior pituitary (2)

A

syndrome of inappropriate ADH : excessive ADH cause water retention
paraneoplasia (small cell carcinoma) : ectopic ADH secretion

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8
Q
  1. Pathology of the hypothalamic-hypophysis system

hypofunction of posterior pituitary

A

Diabetes insipidus (due to decreased ADH)

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